Nano copolymer fibrous membrane material capable of being biodegraded and absorbed and preparation process and use thereof

Abstract

The invention relates to a gelatin nanometer fiber film which can biologically degrade and absorb, and relative preparation, wherein it via the control on static spin realizes the static spin on gelatin water solution and gelatin / macromolecule mixture water, to obtain the nanometer fiber, which comprises: 0 A61L 27 / 14 A61K 45 / 00 D01D 5 / 00 D01F 1 / 00 A61L 27 / 60 A61L 33 / 06 A61L 24 / 04 A61L 15 / 22 A61F 2 / 02 2 14 3 2005 / 11 / 9 1961974 2007 / 5 / 16 000000000 Institute of Chemistry Chinese Academy of Science Beijing 100080 Han Zhichao He Aihua Li Junxing libai 31002 Shanghai Patent Agency of the Chinese Academy of Sciences No.319 Yueyang Road, Shanghai 200031

Description

technical field [0001] The invention belongs to the field of biodegradable and bioabsorbable polymer non-woven fabric materials, in particular to a biodegradable and bioabsorbable gelatin-based nanofiber membrane material and its preparation method and application. Background technique [0002] Electrospinning is a simple and effective process for preparing polymer ultrafine fibers. The principle of this method is that the polymer fluid is charged with thousands to tens of thousands of volts of high-voltage static electricity, and the charged polymer droplets form a Taylor cone under the action of the electric field force, and are accelerated at the apex of the cone. When the electric field is strong enough , the polymer droplets overcome the surface tension to form a jet stream, which forms various forms of unstable flow in the air and finally falls on the grounded receiving device. According to the different receiving devices, it can form a non-woven fabric or A polymer f...

AI Technical Summary

Problems solved by technology

At present, several documents and patents about gelatin dry or wet spinning have been reported, but the gelatin and gelatin-based composite fibers prepared by the prior art generally have a relatively thick diameter (greater than 10 microns), which is limited. The further wide application of gelatin in the field of biomedicine

Electrospinning method is an effective means to prepare ultrafine fibers, but because the aqueous solution of pure gelatin is in a colloidal state at room temperature, and because gelatin is not easily soluble in general organic solvents, it is difficult to perform electrospinning on gelatin. There are only a few reports on the electrospinning of gelatin in some organic fluorinated solvents (Polymer, 2004, 45: 5361-5368; J.Biomed.Mater.Res., 2005, 72B, 156-165; Polymer, 2005 , 46, 5094~5120.), but this method has problems such as expensive solvents, high toxicity of organic solvents, difficulty in completely removing residual organic solvents, and difficulty in solvent recovery, which limits the further application of gelatin nanofibers

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