Novel skin care compositions

Abstract

Skin care compositions are provided comprising a highly hydrophobic substance, an alkaryl polyfluorocarbon, particularly a substituted phenyl-polyfluoroacylamino propanamide, an alkanol and refined oils and the oil triglyceride fractions in sufficient amount to provide substantial homogeneity. When employed for hirsutism, optionally antioxidants and moisturizer are added. For use against wrinkles, additionally vitamins, antioxidants and a mixture of extracts of naturally occurring substances are present.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This application claims priority from U.S. Provisional Patent Application No. 60 / 713,882 filed on Sep. 1, 2005, which is hereby incorporated by reference in its entirety.STATEMENT OF GOVERNMENTAL SUPPORT [0002] This invention was not made with Government Support.REFERENCE TO SEQUENCE LISTING, COMPUTER PROGRAM, OR COMPACT DISK [0003] None. BACKGROUND OF THE INVENTION [0004] 1. Field of the Invention [0005] The field of this invention concerns cosmetic compositions, particularly skin care related to skin hormonal imbalance. [0006] 2. Related Art BACKGROUND [0007] Mammalian skin and associated characteristics, such as wrinkles and hair growth and loss, are significantly affected by hormones, and the individual skin responsiveness to their levels and ratios, since there is substantial interest in the treatment of skin and its associated characteristics, there have been numerous reports of treatment as palliatives and cures. 1. Wrinkle Redu...

AI Technical Summary

Benefits of technology

"The patent describes a cosmetic skincare product that can be applied to reduce wrinkles and hirsutism (excessive facial hair growth). The product contains a special ingredient called a substituted highly hydrophobic substance that is combined with a physiologically acceptable lower alkanol and solubilizing additives. The product is applied topically and quickly absorbed into the skin, providing the desired results without being systemically resorbed."

Problems solved by technology

Wrinkles are skin folds and creases caused by dermal thinning and loss of elasticity, which is a result of the aging process and / or exposure to noxious substances and / or physical factors such as UV radiation, all of which adversely affect the skin metabolism.

There are many claims to inventions for non-surgical wrinkle reduction or removal, but there are few systematic studies to support such claims.

There is a plethora of facial creams available containing a variety of substances, many of which are either inefficient or induce side effects at the levels of efficacy.

Thus, it is known that topical vitamin C, tretinoin, or isotretinoin, while transiently improving the wrinkles caused by aging and photo damage, have a considerable incidence of irritation.

Inducing paresis of the muscle fibers for cosmetic purposes by substances blocking the neuromuscular junctions is not physiologically acceptable and has its own particular toxicity.

However, giving mammalian estrogens systemically for the sole purpose of reducing the signs of skin aging would not be medically defensible.

Therefore, topical mammalian estrogens for skin regeneration, although effective, cannot qualify as a cosmetic preparation and are not authorized in cosmetic creams.

However, in a topical application they are not resorbed systemically (Bayerl and Keil, 2002 Akt Dermatol 28:14-8).

IH is considered a skin hyperandrogenetic syndrome in the cosmetic category since especially dark excessive facial hair is visible and leads to psychological distress.

Cyproterone acetate (CPA), a progestagen with anti-androgenic properties, carries the risk of hypertension, thromboembolism, diabetes mellitus, hypercholesterolemia and endometrial cancer.

Mechanical depilation by tweezing and depilatory can potentially exacerbate IH by stimulating the growth of thicker and coarser hair, making subsequent treatments more difficult and occasionally inducing folliculitis and trauma to the hair shaft and skin.

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