Therapeutic compositions and methods of treatment with capsianoside-type compounds

US20080103102A1Inactive Publication Date: 2008-05-01BMB PATENT HLDG CORP
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
BMB PATENT HLDG CORP
Publication Date
2008-05-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention discloses the use of certain compounds as therapeutic agents, and in particular as analgesics and anti-inflammatory agents. Such compounds include, for example, certain diterpene monoglycosides and diterpene diglycosides. The compounds of the present invention may be synthesized or isolated from the fruit of the genus Capsicum, and in particular may be isolated from sweet bell peppers (C. annuum). Pharmaceutically-acceptable salts, enantiomers, diasteriomers, racemic mixtures, enantiomerically-enriched mixtures, solvates, and prodrugs of such compounds are also disclosed. Pharmaceutical compositions and methods of using such compounds, including pharmaceutical compositions and methods of using such compounds in combination with one or more active ingredients, are also disclosed.
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Description

RELATED APPLICATION DATA

[0001] This application claims priority to U.S. Provisional Patent Application No. 60 / 863,302, filed on Oct. 27, 2006, the entirety of which is hereby incorporated by reference.FIELD OF THE INVENTION

[0002] The present invention relates to analgesic compositions and methods with compounds known as capsianosides and related compounds. The compounds may be synthesized or they may be isolated from the fruit of the genus Capsicum, in particular Capsicum annuum. This invention further relates to the therapeutic uses of such compounds as analgesics and as anti-inflammatory agents. BACKGROUND OF RELATED TECHNOLOGY

[0003] A primary focus of drug research is the development of analgesics for pain management. Analgesics render sensory pathways insensible or less sensible to pain, whereas anesthetics act on all sensory pathways rendering them insensible to pain, temperature, touch, proprioception and skeletal muscle tone. As such, although anesthetics can be used for p...

Claims

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