Microorganism producing o-phosphoserine and method of producing l-cysteine or derivatives thereof from o-phosphoserine using the same

a technology of o-phosphoserine and microorganisms, which is applied in the direction of microorganisms, enzymology, transferases, etc., can solve the problems of difficult industrial application of the conversion process, strong user aversion, and environmental pollution, and achieves high yield and higher production efficiency
US20120190081A1Inactive Publication Date: 2012-07-26CJ CHEILJEDANG CORP
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
CJ CHEILJEDANG CORP
Publication Date
2012-07-26
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having the properties noted above are also provided herein.
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Description

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims the priority benefit of Korean Patent Application Nos. 10-2011-0086081, filed Aug. 26, 2011 and 10-2010-0102664, filed Oct. 20, 2010. The contents of these patent applications are incorporated herein by reference in their entireties.STATEMENT REGARDING SEQUENCE LISTING

[0002] The Sequence Listing associated with this application is provided in text format in lieu of a paper copy, and is hereby incorporated by reference into the specification. The name of the text file containing the Sequence Listing is HANO—004—00US_ST25.txt. The text file is 28 KB, was created on Oct. 20, 2011, and is being submitted electronically via EFS-Web.TECHNICAL FIELD

[0003] The present invention relates to a method for production of cysteine or its derivatives using O-phosphoserine as an intermediate and recombinant microorganism for use in production of O-phosphoserine.BACKGROUND ART

[0004] L-cysteine is an amino acid that plays an important r...

Claims

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