40 results about "Complications treatment" patented technology

The invention relates to a drug for reducing blood glucose, regulating blood lipid and treating diabetes mellitus combined with hyperlipidemia and other chronic vascular complications and a preparation method thereof. The drug is total alkaloids which are extracted from traditional Chinese medicine golden thread. The preparation method of the drug comprises the following steps: 1) the golden thread herbal medicine is crushed into coarse powder; 2) 5-10 times of the amount of 60-80 percent ethanol is used for carrying out the reflux extraction of the golden thread coarse powder for 1-3 times by 1-2h/time, the filtration is carried out by times, and filtrates are merged. Golden thread extract is obtained by pressure reduction concentration and drying; 3) the golden thread extract is added in 5 times of the amount of 0.5 percent sulfuric acid for dissolution and filtration, the filtrates are respectively regulated to pH9 by lime milk, filtrated and respectively regulated to pH1-2 by hydrochloric acid, sodium chloride is added to allow the salt content to be 10 percent, and the total alkaloids of the golden thread are obtained by even shaking and still placement. Or the golden thread extract is used for separating and purifying the total alkaloids of the golden thread by macroporous resin method. The drying is carried out, and the total alkaloids of the golden thread are prepared into oral formulation or injection formulation. The drug has prominent efficacy for the diabetes mellitus combined with hyperlipidemia and other chronic vascular complications.

The invention belongs to the technical field of drugs for treating diabetes and provides a traditional Chinese medicine preparation for treating diabetic complications in order to solve the problem of various complications existing in the process that diabetic patients are treated through orally taking traditional Chinese medicines and western medicines and injecting insulin at present. The traditional Chinese medicine preparation is prepared from mulberry leaves, ginkgo leaves, seabuckthorn leaves, schisandra chinensis, common yam rhizome, chrysanthemum morifolium, bitter gourd, bitter tartary buckwheat, mulberry twig, astragalus, tuckahoe, danshen, radix puerariae, semen cassiae, mulberries, rhizoma alismatis, pseudo-ginseng and rhizoma coptidis according to a certain proportion. The traditional Chinese medicine preparation can be used for slowly reducing blood glucose and effectively preventing and delaying the occurrence and development of diabetic complications, and is remarkable in effect on treating complications caused by diabetes while assisting in reducing the blood glucose and increasing the glucose tolerance; and in addition, the traditional Chinese medicine preparation can be used for softening blood vessels, promoting the microcirculation of blood, regulating the intestine and stomach functions, improving the mental condition and the sleeping quality, effectively reducing the risks for developing the diabetic complications, reducing the economic burdens of patients and improving the physical conditions and living quality of the patients.

The invention discloses traditional Chinese medicine composition for treating metabolic syndrome. The traditional Chinese medicine composition consists of the following components: radix Angelica sinensis, radix notoginseng, radix ginseng, rhizoma alismatis, folium nelumbinis, fructus mume, fiveleaf gynostemma herb, semen cassiae, bulbus allii macrostemi, cassia twig, fructus aurantii immaturus, radix saliviae miltiorrizae, rhizoma coptidis, fructus crataegi, cactus, semen raphani, semen litchi, radix astragali, aloes, poria cocos, radix stephaniae tetrandrae, cortex cinnamomi, squama manis, radix curcumae, herba leonuri, fructus amomi, radix puerariae, folium lycii, radix bupleuri, radix rehmaniae recens, fructus corni, rhizoma dioscoreae, radix trichosanthis, herba epimedii, semen strychni, semen plantaginis and the like. According to the traditional Chinese medicine composition, the components are combined and complement each other; the traditional Chinese medicine composition can be effectively used for dialectically treating the metabolic syndrome, improving blood lipid level, relieving insulin resistance and obese state, and the like; and the traditional Chinese medicine composition is convenient to prepare, small in side effect, high in safety and low in price, and provides a technical basis for research and development of metabolic syndrome and complication treatment drugs.

The invention discloses a traditional Chinese medicinal composition for treating metabolic syndrome. The traditional Chinese medicinal composition consists of the following components: radix angelicae sinensis, radix notoginseng, ginseng, rhizoma alismatis, lotus leaves, dark plums, fiveleaf gynostemma herb, semen cassiae, platycodon root, liquorice root, fructus xanthii, bulbus allii macrostemi, cassia twig, radix paeoniae alba, radix salviae miltiorrhizae, rhizoma coptidis, fructus crataegi, herba houttuyniae, peach kernels, semen raphani, semen litchi, radix astragali, common dayflower herb, honeysuckle flowers, dandelion, mung beans, aloe, poria cocos, radix stephaniae tetrandrae, herba dianthi, lagenaria siceraria, radix curcumae, herba leonuri, fructus amomi, radix puerariae and folium lycii. The traditional Chinese medicinal composition disclosed by the invention, through the compatibility of the various medicines which complement each other, is effectively applicable to the dialectical treatment of the metabolic syndrome, and the traditional Chinese medicinal composition is capable of improving blood lipid level, relieving insulin resistance and obesity state, and the like. The traditional Chinese medicinal composition disclosed by the invention is convenient to prepare, low in side effect, high in safety and low in cost; and the traditional Chinese medicinal composition provides a technical basis for the research and development of medicines for treating integral metabolic syndrome and complications thereof.

The invention relates to a Medicine for treating diabetes and its complications and process for preparation, which comprises (by weight portions) ginseng 2-20, leech 1-10, ground beetle 2-20, earthworm 2-21, notoginseng 1-25, radix salvia miltiorrhiza 4-30, red peony root 4-23, ligustrum japonicum 3-28, root of balloonflower 2-20, arctium fruit 4-22, atractylodes rhizome 1-20. The invention also relates to the process for preparing various preparations of the medicament.

The invention discloses a medicine composition with active components of carvedilol and a medicinal salt thereof, and fimasartan. The invention also relates to an application of the medicine composition in treating hypertension and complications thereof, and an application of the medicine composition in treating congestive cardiac failure. In the medicine composition, a weight ratio of carvedilol and medicinal salt thereof to fimasartan is 1:0.01-1000. The components of the medicine composition are clear. When the medicine composition is used for treating hypertension and complications thereof, a substantial synergetic effect of the two medicine components is shown, and stable reduction of blood pressure can be realized; when the medicine composition is used for treating congestive cardiac failure, various cardiac indexes are substantially enhanced, a treatment effect is substantial, and a substantial synergetic effect of the two medicine components is shown.

The invention refers to a deproteinized extraction of yak blood, the extracting method and the application. It is a physiological component, the molecular weight less than 5000 or 6000 Daltons; the purification process: collect yak blood on axenic condition, separate out blood serum, filter by Milipore ultrafilter, then sterilize and freeze out the ultrafiltrate. It can be used as drug, health food and food for curing diabetes and syndrome of diabetes, and for preventing and curing variou incomplete brain functions such as senile dementia, extracranial wound, brain coma, etc.

The system disclosed allows a user to specify an illness, disease, or health condition, mental or physical or otherwise, and interconnect with other users having similar diagnoses, symptoms, conditions, complications, treatments, or otherwise. The patient user may be connected to a caregiver who links into the system to connect with other caregivers as well. The social network is a health web designed to interconnect patients, friends, families, doctors or others who seek personalized medical information pertaining to the experiences of others. The system allows an interconnection of patients who want to correspond as to symptoms and treatments, and/or for medical professionals who seek to expand their global knowledge base as to collegial networks for diagnosis, treatment, and real-time evaluation. The social network provides a global interface, connected via mobile device, remotely for medical treatment globally, from the latest innovations in medicine to the remote locations of the world.

The invention belongs to the technical field of biology, and specifically relates to a combined drug for treating diabetes mellitus and complications and a pharmaceutical composition of the combined drug. The invention discloses combined use of components (i): a compound represented by a general formula (I), pharmaceutical salt of the compound and isomers of the compound and the pharmaceutical salt and a component (ii): an SGLT2 inhibitor in preparation of drugs for preventing and/or treating the diabetes mellitus and/or the complications of the diabetes mellitus, and further discloses the pharmaceutical composition containing the components (i) and the component (ii). The combined drug is capable of synergetically reducing blood sugar of db/db diabetic mice, generating an unexpected synergetic effect, improving blood lipid indexes, particularly improving content of triglyceride in serum and further generating a combined effect in aspects of control of body weight and protection of blood lipid, blood pressure, livers and kidneys, so that more benefits are brought to prevention and/or treatment of the diabetes mellitus and the complications including cardiovascular and cerebrovascular diseases, kidney diseases and hepatic diseases.

The invention discloses a simple percutaneous lung puncture and puncture complication treating tool. The tool comprises a positioning needle and a switching mechanism, wherein the positioning needle comprises a needle head and a soft tube, the needle head is connected to one end of the soft tube, the soft tube is sleeved by a coaxial puncture needle sleeve, and a biopsy needle insertion hole, a medicament feeding hole capable of being communicated with the soft tube, and an air flow guide tube are arranged on the switching mechanism. The tool has the various functions including anesthetization, puncture sampling, complication treatment and the like, the functions can be flexibly switched according to the demands, the complications occurring after puncture can be conveniently coped with in time, with the adoption of the tool provided by the invention, the percutaneous lung puncture and complication treating operation efficiencies can be improved, and the additional injury caused to patients during the percutaneous lung puncture and the complication treating operation can be alleviated.

The invention discloses the application of a traditional Chinese medicines formula in preparing drugs treating metabolic syndrome, in particular to the application of traditional Chinese medicines formula formed by three kinds of crude drugs comprising astragalus, semen litchi and lotus leaf, extract powder or the active ingredients in preparing the drugs and to the application in preparing drugs improving at least one symptom of insulin resistance, abnormal glucose metabolism, hypertension, obesity and lipids disorder. The application of a traditional Chinese medicines formula has the advantages of playing effective compatible role of the traditional Chinese medicine ingredient, not only being used as preparing drugs treating each kind of disease of metabolic syndrome, but also providing technical base for research and development aiming at the integrity of the metabolic syndrome and complicating disease and providing safe, effective and economic technical base for nationally preventing metabolic syndrome.

The present invention provides methods of inhibiting the development or progression of atherosclerotic, microvascular, or neurologic disease due to diabetes or insulin resistance in a mammal, or conditions resulting therefrom. The methods involve specifically inhibitingpoly(ADP-ribose) polymerase (PARP) activity or accumulation in the mammal. Also provided are antibodies that specifically react with Nα-acetyl-Nδ (5-hydro-5-methyl)4-imidazolone. Additionally, the invention provides methods of monitoring the effectiveness of an anti-diabetic or anti-insulin resistance treatment or an anti-diabetic or anti-insulin resistance complication treatment in a mammal. The methods involve measuring ADP-ribosylated protein levels, or measuring methylglyoxyl AGE levels in the mammal using an antibodies that specifically react with Nα-acetyl-Nδ (5-hydro-5-methyl)4-imidazolone, or measuring GlcNAc-modified protein levels in the mammal.

The invention discloses a breast cancer postoperative complication treating brace. The breast cancer postoperative complication treating brace comprises a thoracic wall pressurizing support, an armpitpressurizing support and a wearable breast cancer postoperative dressing fixing belt, wherein the thoracic wall pressurizing support is in a flat cushion structure; the armpit pressurizing support isin an ellipsoid structure and comprises a soft external layer and a hard internal core, and the hard internal core is arranged inside and fixedly connected with the soft external layer; the surface of the thoracic wall pressuring support and the soft external layer of the armpit pressurizing support are provided with anti-slippery structures; the wearable breast cancer postoperative dressing fixing belt is composed of an armpit-shoulder binding belt, a breast binding belt, an armpit-shoulder binding belt length adjusting device and a breast binding belt length adjusting device, and the armpit-shoulder binding belt and the breast binding belt penetrate through the armpit-shoulder binding belt length adjusting device and the breast binding belt length adjusting device respectively for adjusting the length; the wearable breast cancer postoperative dressing fixing belt can press the thoracic wall pressurizing support and the armpit pressurizing support onto a wounded part.

The invention discloses an intelligent blood activation instrument which is short for medical intelligent 'ultraviolet blood irradiation and oxygenation (UBIO) '. The intelligent blood activation instrument can be used for clinical treatment of bacterial, fungal and viral infections, immunocompromise, poisoning and the like. The novel coronavirus (COVID-19) is a virus and still a virus after variation, and can be effectively treated by ultraviolet irradiation according to the virus characteristics. UBIO is also effective in the treatment of ischemia, hypoxia diseases, diabetes and complications. The intelligent blood activation instrument is formed by a reciprocating blood circulation system, an oxygen delivery and ventilation system, an ultraviolet irradiation system, a mobile blood activation chamber bracket system and a software working program system of the intelligent blood activation instrument. The intelligent blood activation instrument is characterized in that closed blood reciprocating circulation ultraviolet irradiation is automatically and continuously carried out, and medical specifications are fulfilled.

The invention belongs to the technical field of Chinese medicaments, and particularly relates to a formula of a Chinese medicament for treating hemodialysis complications. The Chinese medicament is prepared from the following Chinese medicinal raw materials in parts by weight: 3-5 parts of angelica, 2-5 parts of broom cypress fruit, 2-4 parts of dendrobe, 3-5 parts of fimbriae orostachys, 2-4 parts of boschniakia rossica, 3-5 parts of siraitia grosvenorii, 3-5 parts of hippocampus, 3-5 parts of polygonum cuspidatum, 3-5 parts of Clematis huchouensis Tamura, 1-3 parts of Ventilago leiocarpa Benth, 1-3 parts of lily of the valley, 2-4 parts of platycodon grandiflorum, 2-4 parts of lespedeza cuneata, 3-5 parts of eucommia bark and 3-5 parts of buckwheat. The Chinese medicament prepared from compatible medicaments has the effects of strengthening the middle warmer and benefiting vital energy, strengthening spleen and benefiting kidneys, promoting blood circulation and detoxifying, has a significant treatment effect on complications after renal dialysis, is safe, does not have toxic or side effect, and provides a guarantee for life safety of renal dialysis patients.