The invention belongs to the technical field of
traditional Chinese medicine wine preparation, and particularly relates to
traditional Chinese medicine compound
wine and a preparation method thereof. The
traditional Chinese medicine compound
wine is prepared from the following raw materials in specific parts by weight: rhizoma polygonati, Chinese yam, raspberry, fructus lycii, cinnamon,
astragalus membranaceus and the like through base wine extraction. The preparation method comprises the following steps: pretreating raw materials, mixing the pretreated raw materials with base liquor, sequentially carrying out ultrasonic treatment, composite
enzymatic hydrolysis under a weak acid condition and
reflux extraction to promote the
nucleophilic addition of cinnamyl
aldehyde,
citral,
polygonatum polysaccharide and Chinese yam
saponin to form a
hemiacetal structure, and cooperating with
organic acid and
polysaccharide to construct a
hydrogen bond network to form a stable
compound system; and filtering the extracting solution, carrying out stepped variable-temperature aging, blending and filling to obtain the traditional Chinese
medicine compound wine. The
dissolution rate and stability of active ingredients are effectively improved, the problems that traditional medicinal liquor is prone to
precipitation, low in
bioavailability and poor in taste are solved, and meanwhile the traditional Chinese medicinal liquor has the comprehensive effects of improving the
immunity, moistening the
lung, nourishing yin and tonifying yang.