The invention discloses a manned spaceship capsule work room which comprises a cabin, a capsule, a capsule chamber, a sealing door, an inner cabin door, an outer cabin door and a compressing gas tank. The manned spaceship capsule work room is characterized in that the interior of the spaceship is separated into the cabin and the capsule chamber by the inner cabin door, equipment of a spacecraft in the prior art and astronauts are intensely and compactly arranged in the cabin, the capsule that is folded and is in butt joint with the outer cabin door from an inner side is arranged in the capsule chamber, after lift-off, the capsule expands outward via air inflation, so as to form a huge space of which the air pressure is equal to that of the cabin. Compared with the prior art, the manned spaceship capsule work room has more compact and intense spaceship lift-off process design and a smaller volume, opens the capsule work room after the lift-off, and has a larger living and working space, the flexible capsule has strong plasticity and remolding performance, functional zones can be separated or divided according to multiple requirements, and simultaneously, the flexible capsule has better elastic variable performance, and thus can better resist the destruction caused by the impact of space debris and loose bodies in space. Therefore, the manned spaceship capsule work room has a very good application prospect.