Medication for treating obstruction of qi in the chest

A technology for chest pain and heart pain and medicine, which is applied in the field of medicine, can solve the problems of low degree of pure naturalness, low degree of naturalness, and low degree of pureness of dropping pill excipients, so as to reduce the irritating smell of medicines, improve the pH of the oral cavity, and achieve pure naturalness. high degree of effect

Inactive Publication Date: 2008-10-01
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] With the global expansion of the market and the requirement of human beings to return to nature, the use of drugs with low toxicity and side effects, especially pure natural drugs, has become the first choice of people. The dropping pill preparation is a new type of Chinese medicine preparation with high efficiency and quick effect. The shortcomings and deficiencies of traditional Chinese medicine preparations in the past, but the current drop pill preparations generally face the following problems: 1. The drop pill auxiliary materials are not purely natural: at present, most of the drop pill base auxiliary materials are chemically synthesized, and the natural degree is low. New alternatives The search for matrix excipients, especially the search for alternative matrix excipients with a high degree of naturalness and the determination of their preparation process, is also very difficult, because the preparation conditions required for common and possible substitutes for natural matrix excipients are very harsh. And its dripping pill dripping conditions are the key to affect the preparation of dripping pills
If the melting temperature of the excipient is too high, the viscosity will be low and the plasticity will be poor. If the melting temperature of the excipient is too low, although the plasticity is strong, the dropping pills have disadvantages such as easy sticking and deformation. The accessories are very hard work
2. Problems encountered in the export of dripping pills: With the development of the economy, the market is becoming more and more internationalized, and China is also trying to adapt to this trend. Currently, Chinese medicine dripping pills, which are used as health food, have been successfully exported to many countries, but There are also many problems at present, because different countries have different approvals for the excipients selected for the preparation of Chinese medicine dripping pills, especially in Europe with developed industries, which have stricter regulations on food excipients and pharmaceutical excipients, and the drops exported as health food The chemically synthesized auxiliary materials (such as polyethylene glycol) selected for pill preparations are not listed in the food additive catalogs of some countries, which is very unfavorable for Chinese medicine dripping pill preparations to enter the international market, and has become a stumbling block for Chin

Method used

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  • Medication for treating obstruction of qi in the chest
  • Medication for treating obstruction of qi in the chest
  • Medication for treating obstruction of qi in the chest

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] (a): Take 39.2g cinnamon, 392.4g Chuanxiong, 235.4g Rhizoma Cyperi (stir-fried with vinegar), 417g xylitol, and 83g starch for later use;

[0077] (b) Cinnamon, Rhizoma Chuanxiong, extract volatile oil, collect the volatile oil in another device, decoct the dregs in water for two times, the first time is 2.5 hours, the second time is 2 hours, combine the decoction, concentrate until the relative density at 50 ° C is 1.25, add an equal amount of ethanol to precipitate, absorb the supernatant, filter, and use the filtrate for later use;

[0078] (c) Get Rhizoma Cyperi, prepare its active ingredient according to the percolation method under Chinese Pharmacopoeia 95 edition appendix 10 fluid extract and extract item, make solvent with 80% ethanol, carry out percolation after soaking for 24 hours, collect percolation liquid About 2000ml, combined with cinnamon and Chuanxiong filtrate, recovered ethanol, concentrated to 70ml;

[0079] (d) Take the volatile oil, add an approp...

Embodiment 2

[0082] (a): Take 39.2g cinnamon, 392.4g Chuanxiong, 235.4g Rhizoma Cyperi (stir-fried with vinegar), 385g lactitol, and 115g starch for later use;

[0083] (b) Cinnamon, Rhizoma Chuanxiong, extract volatile oil, collect the volatile oil in another device, decoct the dregs in water twice, the first time is 2.5 hours, the second time is 2 hours, combine the decoction, concentrate until the relative density at 50 ° C is 1.25, add an equal amount of ethanol to precipitate, absorb the supernatant, filter, and use the filtrate for later use;

[0084] (c) Get Rhizoma Cyperi, prepare its active ingredient according to the percolation method under Chinese Pharmacopoeia 95 edition appendix 10 fluid extract and extract item, make solvent with 80% ethanol, carry out percolation after soaking for 24 hours, collect percolation liquid About 2000ml, combined with cinnamon and Chuanxiong filtrate, recovered ethanol, concentrated to 70ml;

[0085] (d) Take the volatile oil, add an appropriate ...

Embodiment 3

[0088] (a): Take 39.2g cinnamon, 392.4g Chuanxiong, 235.4g Rhizoma Cyperi (stir-fried with vinegar), 357g xylitol, and 143g gum arabic for later use;

[0089] (b) Cinnamon, Rhizoma Chuanxiong, extract volatile oil, collect the volatile oil in another device, decoct the dregs in water twice, the first time is 2.5 hours, the second time is 2 hours, combine the decoction, concentrate until the relative density at 50 ° C is 1.25, add an equal amount of ethanol to precipitate, absorb the supernatant, filter, and use the filtrate for later use;

[0090] (c) Get Rhizoma Cyperi, prepare its active ingredient according to the percolation method under Chinese Pharmacopoeia 95 edition appendix 10 fluid extract and extract item, make solvent with 80% ethanol, carry out percolation after soaking for 24 hours, collect percolation liquid About 2000ml, combined with cinnamon and Chuanxiong filtrate, recovered ethanol, concentrated to 70ml;

[0091] (d) Take the volatile oil, add an appropria...

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Abstract

A medicine for treating the obstruction of Qi ni the chest and angina pectoris is disclosed. Its advantages are high safety and lower toxic by-effect.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a pharmaceutical preparation for treating chest pain and heartache made from traditional Chinese medicines. Background technique [0002] Chest obstruction (cardiac pain) refers to insufficient chest yang, yin-cold, turbid phlegm remaining in the chest, or insufficient heart-qi, agitation and weakness, resulting in blockage of qi and blood, and loss of blood nourishment for the heart. This disease is a visceral arthralgia disease mainly manifested by chest tightness and paroxysmal cardiothoracic pain. Primary disease is equivalent to the angina pectoris of the claimed coronary heart disease of modern medicine. At present, the commonly used drugs for the treatment of coronary heart disease angina pectoris: Chinese patent medicines include Compound Danshen Tablets and Danqi Tablets, western medicines include long-acting nitroglycerin, dipyridamole: aspirin, etc. The total effective rate o...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61K36/54A61K36/236A61K9/20A61P9/10
Inventor 李永强陈建明祝国光郑永锋朱永宏李旭章顺楠刘金平叶正良魏峰
Owner TIANJIN TASLY PHARMA CO LTD
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