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Traditional Chinese medicine preparation for preventing respiratory viral infection disease and preparation method

A technology of traditional Chinese medicine preparations and virus infection, which is applied in the direction of respiratory diseases, antiviral agents, medical formulas, etc., can solve the problems of restricting traditional Chinese medicines, and achieve the effects of fast mucosal absorption, rapid onset of effect, good antiviral and antibacterial effects

Inactive Publication Date: 2008-01-16
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, traditional Chinese medicine is limited to a large extent to play an important role in the prevention of respiratory viral infectious diseases.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The composition of embodiment 1, Cangguo spray

[0021] Atractylodes 8g, Tsaoguo 10g, Schizonepeta 10g, Cyrrhizae 10g, Mint 10g, Huoxiang 6g, Clove 2g, Borneol 0.10g.

Embodiment 2

[0022] Embodiment 2, the preparation of Cangguo spray

[0023] Weigh cloves of the above weight and add 10 times the amount of water, steam distillation to extract the volatile oil, and separate the clove volatile oil with an oil-water separator; then add 15 to the 6 flavors of Atractylodes atractylodis, Tsaoguo, Nepeta, Cyperus, Peppermint, and Huoxiang according to the above weight. Doubling the amount of water, steam distillation to extract the volatile oil, and the oil-water separator to separate the volatile oil. Combine the obtained volatile oils, add borneol to dissolve the volatile oils, and obtain the total volatile oils. For every 60g of volatile oil, add 580ml of ethanol, 100g of glycerin, 1ml of linalool, and add water to 1000ml. Add the excipients. Use the stirring and mixing process to evenly disperse the raw materials and excipients into the solvent, and then put them into a plastic spray bottle.

Embodiment 3

[0024] Embodiment 3, the antiviral effect of Cangguo spray

[0025] (1) In vitro antiviral test of Cangguo spray

[0026] 1 Experimental materials

[0027] 1.1 Drugs: Cangguo spray oil is provided by the New Drug Research and Development Center of Nanjing University of Traditional Chinese Medicine.

[0028] 1.2 Viruses: Influenza A virus FM1 strain, hemagglutination titer 1:1280; parainfluenza virus Sendai strain, hemagglutination titer 1:640; rhinovirus N36 strain, isolated and identified for adult common cold, all at -80°C Store in a low temperature refrigerator for later use.

[0029] 1.3 Cells: Human embryonic skin muscle fibroblasts, the 4th to 6th passage, are self-established strains in our laboratory.

[0030] 1.4 Chicken embryo: 9 days old.

[0031] 1.5 Pork blood cells: collect fresh pork blood and prepare 0.5% blood cell suspension for hemagglutination determination.

[0032] 2 Experimental methods

[0033] 2.1 The virus used was taken out from the low-tempera...

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Abstract

The invention discloses the traditional Chinese medicine preparation for preventing respiratory tract viral infection diseases, which is prepared by medicinal materials such as atractylis, fructus tsaoko, hairy kind of sage, haichow elsholtzia, peppermint, wrinkled gianthyssop, clove and camphol being assigned by certain weight ratios; the preparation method is that: the clove is added with water, then the volatile oil is extracted by steam distillation; weighed six grams of atractylis, fructus tsaoko, hairy kind of sage, haichow elsholtzia, peppermint and wrinkled gianthyssop are added with water, then the volatile oil is extracted by steam distillation; then camphol is added to the combination of the volatile oil produced from the above two steps for dissolving in the volatile oil, and then the volatile oil is completed. Finally, every sixty grams of volatile oil is added with five hundred and eighty milliliters of ethanol, one hundred grams of glycerin and one milliliter of linalool, and then is added with the assistant materials when the volatile oil achieves one thousand milliliters by adding water, the material medicine and the assistant materials are fully mixed round so as to be evenly dispersed in the solvent, then the spray can be made by filling the mixture into the plastic spraying bottle, the invention has good antivirus and anti-bacteria functions, and can enhance the cellular immunity and humoral immunity functions of the antibody.

Description

1. Technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a medicine for preventing respiratory viral infectious diseases prepared from Chinese herbal medicines. 2. Background technology [0002] Respiratory tract infectious diseases (including a variety of acute infectious diseases) have always been common clinical diseases and frequently-occurring diseases, accounting for about 1 / 4 of internal diseases, seriously threatening people's health and even life. So far, the number of deaths due to respiratory diseases still ranks first among the causes of death. The pathogenic microorganisms of respiratory tract infection involve bacteria, viruses, mycoplasma, chlamydia and other types. In particular, viral infections are particularly difficult to prevent and treat. Some of them have not yet found specific or effective treatments. It spreads rapidly, has serious pathological damage, and has complex and diverse condi...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/12A61P11/00A61P31/12
Inventor 杨进龚婕宁彭国平魏凯峰张庆宏郭海唐元瑜
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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