Medical tectorial membrane shaped radiation NiTi alloy endovascular stent

An inner stent and conformal technology, applied in the field of medical devices, can solve the problem of ineffective inhibition of tumor growth and thrombus, and achieve the effects of inhibiting mitosis, better effect and increasing sensitivity

Inactive Publication Date: 2008-04-16
李楠
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a conformal radiation NiTi alloy intravascular stent covered with intima in order to solve many defects such as that the metal intravascular stent in the prior art cannot effectively inhibit tumor growth and is easy to form thrombus. The actual needs of the work, more in line with the actual use requirements

Method used

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  • Medical tectorial membrane shaped radiation NiTi alloy endovascular stent

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Embodiment 1

[0035] The present invention will be described in detail in conjunction with the accompanying drawings and specific embodiments.

[0036] The stent used is a self-expandable NiTi alloy intravascular stent, which is a tubular network structure stent made of NiTi alloy plate with a thickness of 0.1-0.3mm. It is divided into multiple specifications, with a tube diameter of 0.2-2cm and a length of 2-3cm. When used to support the portal vein of the liver, a large-scale stent can be selected, and the diameter of the stent after expansion can reach 2cm.

[0037] The inner wall of the stent is covered with a polyurethane film, and the material used is polycarbonate polyurethane, and the chemotherapeutic drugs are evenly coated on the inner surface of the film by spraying. The selected spray gun is Graco airless or electrostatic spray gun. The drug sprayed is any intravenous chemotherapeutic drug, selected according to the difference in tumor sensitivity: fluorouracil, mitomycin, pirar...

Embodiment 2

[0039] As shown in the figure, when the medical film-covered conformal radiation NiTi alloy stent of the present invention is placed in the stenotic segment of the blood vessel, the self-expandable NiTi alloy stent 1 will automatically expand, stretch the stenotic or obstructed segment, and restore the blood vessel. Patency, improving tissue blood perfusion. Especially when stent 1 is placed in the portal vein or its branches of a patient with liver cancer complicated by portal vein tumor thrombus, one or more imaging scanning devices, such as CT, MRI or PET scans, are performed on the tumor site of the patient to obtain corresponding types of images sequence. The obtained image sequence is transmitted to the tumor radiotherapy planning system, and the 3D image reconstruction is performed on the image sequence through the image fusion method to accurately determine the tumor target area and clarify the natural pipeline in the right upper abdomen area (including the portal vein...

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Abstract

The present invention belongs to the technique category of the medical instrument, relates to a tectorial conformal radiate NiTi alloy vascular inner rack which is implanted to the blood vessel of the human body. To settle the problems of that the existing vascular inner rack can not restrain the growth of the tumour and the thrombus is easy to form, etc., the bracket used by the invention is self-expanding NiTi alloy vascular inner rack, a layer of polycarbonate type polyurethane membrane is covered at the inner wall, the antineoplastic medicine is spraying-coated to the inner surface of the membrane, and the active particles which are used for the inner radiating of the tumour are inserted at the outer bracket of the membrane according to the conformal property. The NiTi alloy vascular inner rack applied by the invention can effectively expand and support the blood vessel; the novel film forming material polycarbonate type polyurethane has an excellent bioavailability; the active particles for the conformal radiotheraphy outside the membrane are inserted to the bracket with a simple and convenient double-buckle mode, the growth surround the blood vessel area is effectively restrained and the radioactive side injury of the normal tissue is reduced. The invention has the advantages of easy making, low cost, strong innovation and wide market prospect.

Description

technical field [0001] The invention belongs to the field of medical equipment, and relates to a metal vascular stent, in particular to a NiTi alloy vascular stent that can be implanted into human blood vessels. The inner wall of the stent is covered with a layer of polyurethane film, and radioactive particles are embedded on the stent according to the radiation conformity. Background technique [0002] At present, the medical metal intravascular stents widely used in clinical medical work are mostly used to treat benign diseases such as coronary vascular and peripheral vascular stenosis, but in clinical practice, solid tumors often invade important blood vessels or directly grow into blood vessels to form tumor thrombi However, placement of conventional endovascular stents can expand and support blood vessels, but cannot control tumor growth. For tumors that have invaded important blood vessels, even if the covered intravascular stent is used, it can only act as a compressi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/02A61L31/08A61L31/16A61P35/00A61F2/82
Inventor 李楠程树群石洁薛捷李昊
Owner 李楠
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