Levamisol hydrochloride compound preparations for eperythrozoonsis for animals and preparation thereof

Abstract

The present invention discloses a veterinary levamisole hydrochloride compound preparation used for the eperythrozoonosis in the biotechnical field and a preparation method thereof. The present invention considers the levamisole hydrochloride, imidocarb dipropionate and artemether as main materials to be matched with magnesium dichloride, 1, 2-propanediol, refined soybean oil, lecithin and glycerin to be processed by the methods of weighing, crushing, stirring, mixing, checking, measuring, packing, etc. Components and weight percentages are: 3 percent to 12 percent of the levamisole hydrochloride, 5 percent to 15 percent of the imidocarb dipropionate, 2 percent to 10 percent of the artemether, 0.5 percent to 5 percent of the magnesium dichloride, 1 percent to 10 percent of the 1, 2-propanediol, 5 percent to 15 percent of the refined soybean oil, 0.5 percent to 1 percent of the lecithin and 2 percent to 5 percent of the glycerin. The compound preparation of the present invention can be medicated by intramuscular injection and subcutaneous injection, which has the characteristics of low cost, stable storage, assured effect and eliminating eperythrozoon thoroughly.

Description

Technical field [0001] The invention relates to a preparation in the field of biological technology and a preparation method thereof, in particular to a veterinary compound preparation of levamisole hydrochloride for eperythrozoon disease and a preparation method thereof. Background technique [0002] Eperythrozoon is a zoonotic disease caused by the parasitism of eperythrozoon on the surface of red blood cells, plasma and bone marrow of humans and animals. Porcine eperythrocytosis mainly causes fever, anemia, jaundice and sow abortion in piglets. The disease is often mixed with other swine diseases. It is difficult to prevent and harm, and it causes huge economic losses to the pig industry. However, because eperythrozoonosis has just attracted the attention of producers in recent years, the theoretical accumulation and clinical experience of its prevention and treatment have just begun. At present, there is no safe, efficient and environmentally friendly specific therapeutic dru...

AI Technical Summary

Problems solved by technology

[0004] Found through literature retrieval to prior art, relevant report is very few, and Huang Shuihong etc. published " the medicine curative effect exploration of porcine eperythrozoon disease " on the 2nd period of " contemporary animal husbandry " in 2004, proposed to use to Eperythrozoon Sensitive drugs "Xuechongjing", sulfa-methoxine sodium, oxytetracycline, chlortetracycline, metronidazole and doxycycline in the treatment of Eperythrozoon disease can reduce the infection intensity of Eperythrozoon to a certain extent, However, none of them can purify the Eperythrozoon in the blood, and the existence of Eperythrozoon can still be detected after the treatment of the disease, and neither can completely remove the Eperythrozoon disease in the blood.