Method for preparing policresulen vaginal tablet and quality control method
A quality control method and polycresol technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, pill delivery, etc., can solve problems such as contaminated clothing, inconvenient use of solutions, melting and loss of suppositories, etc., to promote disease Rehabilitation, high effective drug concentration, and the effect of reducing adverse reactions
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[0018] Example: prescription (1) polycresol sulfaldehyde 90g, lactose 80g, starch 180.0g, kaolin 120g, hypromellose 3.0g, silicon dioxide 20.0g, microcrystalline cellulose 60.0g, cross-linked polyvinyl Ketone 60g (plus 20g), magnesium stearate 4.0g to make 1000 tablets
[0019] (2) Method
[0020] A pretreatment: In addition to polycresol, lactose, starch, kaolin, silicon dioxide, crospovidone, microcrystalline cellulose, and magnesium stearate were respectively passed through a No. 7 sieve.
[0021] B polycresol vaginal tablet granule preparation: take by weighing polycresol and lactose, starch, kaolin, crospovidone 40g, microcrystalline cellulose of prescription quantity, with 2% hypromellose aqueous solution It is used as a binder, granulated with 16 mesh, dried at 60-70°C, granulated with a 16 mesh sieve, added with prescribed amount of magnesium stearate, silicon dioxide and 20 g of crospovidone, and mixed well. Measure the drug content of the granules and calculate the...
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