Process for extracting bacterial cell coenzyme Q10

Abstract

The invention relates to a technology for extracting coenzyme Q10 in bacterial cells, which pertains to the technical field of microbiology engineering. Thalli is automatically and quantitatively put into from the dog-house of a continuous countercurrent device under the control of a weigh-instrument, a solvent is injected from a solvent inlet under the control of a flowmeter and the leaching solution and the thalli form reverse continuous countercurrent leaching process under the push of a shovel-like thruster; the concentration gradient is large, relative movement exists between the solventand the thalli and the thalli moves from the left end to the right end of an extraction container continuously under the function of the shovel-like thruster while the solvent moves from the right end to the left end of the container under the action of pressure; a diffusion boundary layer is thin and fast to be updated and the coenzyme Q10 is extracted after 2 to 10 hours of reaction of the thalli which enters from the left end of the device after the contact of the solvent and the thalli; the thalli enters a rake type dryer from the right end of an extraction device by press treatment and residual organic solvent in the thalli is treated with drying treatment in the rake type dryer; the yield of the coenzyme Q10 reaches more than 90 percent.

Description

technical field

[0001] The invention belongs to the technical field of microbial engineering, in particular to a process for extracting coenzyme Q10 in bacterial cells. Background technique

[0002] Coenzyme Q10 is a chemical component that widely exists in the cells of organisms and has no toxic side effects. It is the basis of energy production in human cells, and has a metabolic cardiotonic effect with definite effects. Coenzyme Q10 is mainly used in the treatment of acute and chronic viral hepatitis and acute hepatic necrosis. It has a very good curative effect on cardiovascular diseases and hypertension. It can also be used in the comprehensive treatment of cancer. etc. are uniquely effective.

[0003] There are four main methods for producing coenzyme Q10 raw materials: biological extraction, solanesol semi-synthesis, chemical synthesis and microbial fermentation, among which microbial fermentation is recognized as the most advantageous and potential technology. The...

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