Controllable sustained-release fine particle of phycobiliprotein and preparation method thereof
The technology of phycobiliprotein and slow-release particles is applied in the fields of food, medicine and health care products, and can solve the problems of limited application and poor stability of phycobiliprotein, and achieve the effects of prolonging storage time, simple and feasible preparation process and good tolerance.
Inactive Publication Date: 2008-10-29
JIMEI UNIV
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Problems solved by technology
However, due to the active nature and poor stability of phycobiliprotein, its application is greatly limited.
Method used
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Embodiment 1
[0025] Example 1: 1% sodium alginate, 0.1% calcium alginate, 0.1% chitosan, and the rest is water.
Embodiment 2
[0026] Example 2: 10% sodium alginate, 10% calcium alginate, 0.1% chitosan, and the rest is water.
Embodiment 3
[0027] Example 3: 5% sodium alginate, 5% calcium alginate, 5% chitosan, and the rest is water.
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Abstract
The invention discloses a controllable slow-released granule of phycobiliprotein, which consists of wall material and core material made from the dry powder of the phycobiliprotein; the weight ratio of the core material to the wall material is 1: 4-8. The weight percentages of each composition of the wall material are 1 percent to 10 percent of sodium alginate, 0.1 percent to 10 percent of calcium alginate and 0.1 percent to 5 percent of chitosan, and the rest is water. The controllable slow-released granule of the phycobiliprotein takes the sodium alginate, calcium alginate and chitosan after extraction and processing as the wall material and takes the dry powder of phycobiliprotein as the core material, and phycobiliprotein micro-capsules are prepared by a method of low-temperature embedding under the acidic condition; thus the prepared controllable slow-released granule of the phycobiliprotein can realize controllable slow releasing in a living organism environment; the preparation technique of the invention is simple and practical, and the prepared wall material is edible and is characterized by being enteric-coated; the controllable slow-released granule of the phycobiliprotein can realize controllable slow releasing, can avoid the environmental influences such as light, heating, acid and alkali, etc., thereby effectively prolonging the storage time of the phycobiliprotein and greatly increasing the stability of the phycobiliprotein.
Description
technical field [0001] The invention belongs to the field of food, medicine and health care products, and in particular relates to a controllable slow-release microparticle of phycobiliprotein and a preparation method thereof. Background technique [0002] Phycobiliproteins are important light-harvesting pigment proteins widely present in cyanobacteria, red algae, cryptophygae and a few dinoflagellates, mainly including phycoerythrin, phycocyanin, phycoerythrocyanin and isophycocyanin. Since the 1980s, scholars from Japan, the United States and other countries have discovered that phycobiliprotein is an important physiologically active substance, which can scavenge free radicals and active oxygen, kill tumor cells; increase the activity of lymphocytes, promote the function of the immune system, and resist various diseases. disease. However, due to the active nature and poor stability of phycobiliprotein, its application is greatly limited. [0003] Microencapsulation techn...
Claims
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IPC IPC(8): A23L1/29A23L1/305A23J3/20A23P1/04A61K36/02A61K9/50A23L33/185A23P10/30
Inventor 郑江
Owner JIMEI UNIV
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