Formula for preparing anti-eczema and cutitis products and preparation method thereof

A technology for eczema dermatitis and formula, which is applied to the formulation and preparation field of anti-eczema dermatitis products, can solve problems such as diagnosis, detection, prevention and protection of eczema dermatitis that have not yet been found.

Inactive Publication Date: 2008-12-31
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

5% doxepin cream can be used 4 times a day, but percutaneous absorption may cause systemic symptoms. Hydroxyzine hydrochloride 25 mg 3 to 4 times a day is also effective (children 2 mg / kg per day, given in divided doses every 6 hours) medicine)
[0107] According to literature search, so far, no other relevant reports have been found on tincture formulations and preparation methods for diagnosis, detection, prevention, protection, treatment and research of eczema dermatitis.

Method used

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  • Formula for preparing anti-eczema and cutitis products and preparation method thereof
  • Formula for preparing anti-eczema and cutitis products and preparation method thereof
  • Formula for preparing anti-eczema and cutitis products and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0452] Embodiment 1, the preparation of this anti-eczema dermatitis product

[0453] The preparation of preferred scheme 6

[0454] 1 Sources and requirements of raw and auxiliary materials:

[0455] Phenol: Manufactured by Tianjin Bodi Chemical Co., Ltd., in line with the standards of Part II of the 2005 edition of the Chinese Pharmacopoeia (page 325). This product is a colorless to red needle-like crystal or crystalline block; has a special odor; has hygroscopicity; the aqueous solution shows a weak acid reaction; the color gradually becomes darker when exposed to light or in the air. The freezing point of this product is not lower than 40°C.

[0456] Menthol: Manufactured by Nantong Mint Factory Co., Ltd., in line with the standard of Part One (284 pages) of the 2005 edition of the Chinese Pharmacopoeia. This product is colorless acicular or prismatic crystal or white crystalline powder; it has the special aroma of mint, and the taste is hot at first and then cool. Etha...

Embodiment 2

[0472] Embodiment 2, dermatitis tincture (preferred scheme 4) clinical application summary

[0473] Abstract OBJECTIVE: To study the safety, feasibility and effect of dermatitis tincture (formula 4) in the clinical treatment of pruritus such as eczema and contact dermatitis. Method: 60 outpatients were selected and randomly divided into test group and control group, 60 cases in the test group and 40 cases in the control group. In the test group, dermatitis tincture was sprayed on the affected area, and cool oil was used as control, 3 to 4 times a day. Changes in skin lesions and itching sensation were observed within one month. Results: Compared with the qingliangyou control group, the total effective rate of eczema, contact dermatitis, skin amyloidosis and chronic prurigo was significantly different (P<0.05). Discussion: This dermatitis tincture has the advantages of convenient use, quick effect, and mild side effects. It is effective and safe for the treatment of eczema, co...

Embodiment 3

[0495] Embodiment 3, dermatitis tincture (preferred scheme 5) clinical application summary

[0496] Abstract OBJECTIVE: To study the safety, feasibility and effect of dermatitis tincture (formulation 5) in the clinical treatment of neurodermatitis, solar dermatitis and atopic dermatitis. Methods: 60 outpatients were selected and randomly divided into test group and control group, 40 cases in the test group and 20 cases in the control group. In the test group, dermatitis tincture was sprayed on the affected area, and cool oil was used as control, 3 to 4 times a day. Changes in skin lesions and itching sensation were observed within one month. Results: Compared with the qingliangyou control group, there were significant differences in the total effective rate of neurodermatitis, solar dermatitis and atopic dermatitis (P<0.05). Discussion: The present invention has the advantages of convenient use, quick effect, safety and no allergy, and is suitable for the treatment of neurode...

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Abstract

The invention relates to a formula for preparing an anti-eczema dermatitis product and the preparation method thereof. The invention adopts dexamethasone, menthol, phenol and boric acid compatibly for external use for the first time and provides an anti-eczema dermatitis product which also has multiple prevention functions of anti-allergy, anti-pruritus, anti-infection, and the like; the formula has the advantages of remarkable and quick antipruritic effect, strong bacteriostasis, small toxic side effect, and positive curative effect; ideal effect can be achieved when the anti-eczema dermatitis product is in direct use; more particularly, the tincture formula thereof has the advantages of stable property, simple preparation technology, safety and effectiveness, good feasibility, high repeatability, and controlled quality, and is suitable for the industrial production. The eczema dermatitis has diverse categories and etiologies, complicated disease diagnosis, and very high incidence and relapse rate; the anti-eczema dermatitis product of the invention has a plurality of usages, can enhance medical effect, is convenient to select in clinic, and can reduce the economic burden of the patients; therefore, with the number of dermatitis patients increasing year by year, the demand for therapeutic medication can be also increased; the formula and the preparation method thereof can produce greater social and economic benefits.

Description

technical field [0001] The invention relates to the technical fields of medicine, food and beverage, in particular to a formula for diagnosing, detecting, preventing, protecting, treating and researching eczema and dermatitis and a preparation method thereof, more specifically to a formula mainly used for Tincture formula and preparation method for diagnosing, detecting, preventing, protecting, treating and researching pruritic skin diseases such as eczema, allergic dermatitis, neurodermatitis, solar dermatitis, atopic dermatitis and related skin diseases directly caused by them . Background technique [0002] (1) Research progress of eczema dermatitis [0003] 1. Eczema [0004] Eczema is a kind of skin inflammation with obvious exudation tendency caused by various internal and external factors. The rash is diverse, but in the chronic stage, it is limited and has invasion and hypertrophy. Itching is severe and easy to recur. [0005] The term eczema has been used for a l...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/06A61K33/22A61P17/00A23L1/30A61K31/045A61K31/05A61K31/573A61K31/661A23L33/10
Inventor 温海张纯刘晓刚朴淑娟林厚文
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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