Tartary buckwheat biological flavone effervescent tablet and preparation method thereof
A technology of bioflavonoids and tartary buckwheat flavonoids is applied in the directions of drug delivery, drug combination, and pharmaceutical formulations, which can solve the problems of increasing product cost and dampness of effervescent tablets, and achieve the effects of preventing moisture absorption and deliquescence, increasing content and reducing production costs.
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Embodiment 1
[0021] 1. Preparation of Tartary Buckwheat Flavonoid Extract
[0022] The dried grains, stems and leaves of tartary buckwheat (1:1 ratio of grains / stems and leaves) were extracted by bio-enzyme combined with water. First use cellulase to carry out enzymatic hydrolysis, the conditions are: temperature 60°C, pH value 6.5, time 1.5 hours, enzyme dosage is 0.1% of the buckwheat dosage (including grains and stems and leaves); after enzymolysis, add water to decoct and extract 3 times , add 8 times the amount of water each time, extract for 30 minutes, filter the extract with a 400-mesh filter cloth, collect the filtrate, and use a decompression device to concentrate the filtrate at 60°C to an extract with a relative density of 1.10-1.20, and then add a concentration of Dissolve it in 30% ethanol, and add it to the chromatographic column equipped with D141 macroporous adsorption resin. After standing for a certain period of time, wash it with distilled water until the effluent is de...
Embodiment 2
[0030] 1. Preparation of Tartary Buckwheat Flavonoid Extract
[0031] The dried grains, stems and leaves of tartary buckwheat (1:1 ratio of grains / stems and leaves) were extracted by bio-enzyme combined with water. First use cellulase to carry out enzymatic hydrolysis, the conditions are: temperature 65 ℃, pH value 6.0, time 1.5 hours, enzyme dosage is 0.2% of tartary buckwheat dosage (including grains and stems and leaves); after enzymolysis, add water to decoct and extract 3 times , add 10 times the amount of water each time, extract for 30 minutes, filter the extract with a 400-mesh filter cloth, collect the filtrate, and use a decompression device to concentrate the filtrate at 60°C to an extract with a relative density of 1.10-1.20, and then add a concentration of Dissolve it in 25% ethanol, and add it to the chromatographic column equipped with D141 macroporous adsorption resin. After standing for a certain period of time, wash it with distilled water until the effluent ...
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