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Biodegradable skull repairing body

A biodegradable and prosthetic technology, applied in the field of biodegradable magnesium alloy prostheses and bone screws, can solve the problem of lack of rights protection, and achieve the effects of good practicability, brain tissue protection, and good bone tissue inducing growth characteristics

Inactive Publication Date: 2009-03-18
INST OF METAL RESEARCH - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the use of degradable magnesium alloy materials has been applied for protection in the patent application, there is no right protection for magnesium alloy as a fully absorbable cranial repair material or its prosthetics and features

Method used

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  • Biodegradable skull repairing body
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  • Biodegradable skull repairing body

Examples

Experimental program
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Effect test

Embodiment 1

[0029] A degradable prosthesis is made of 0.2mm thick AZ31B alloy sheet, such as figure 1 As shown, after the surface is cleaned, the prosthesis is soaked in 5% di-sodium hydrogen phosphate solution for 2 hours, and a layer of phosphate is formed on the surface through a chemical reaction to improve its surface properties.

Embodiment 2

[0031] The 0.08mm thick ZK60 magnesium alloy sheet is processed into a degradable prosthesis, such as figure 2 As shown, after the surface was cleaned, the prosthesis was soaked in a neutral calcium-rich phosphate solution for 3 hours to form a bone-like phosphate layer on the surface and improve tissue compatibility.

Embodiment 3

[0033] A 0.1mm thick AZ21 magnesium alloy sheet is made into a degradable prosthesis, such as image 3 As shown, after the surface is cleaned, the surface layer is doped with nitrogen ions and calcium ions by ion implantation. The thickness of the surface layer is about 0.005mm. After the surface is implanted with nitrogen, the surface properties and corrosion degradation speed of the prosthesis can be improved.

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Abstract

The invention relates to a medical appliance, in particular to a biological degradable magnesium alloy reparation body and a bone screw which are used in skull wound and reshape and restoration. The reparation body and the bone screw are made from biological degradable pure magnesium or magnesium alloy, the reparation body is a thin board or thin slice of 0.03-0.2mm, at least two screw holes used for fixation are arranged on the surface thereof; by surface modification or coating, the bioactivity coat can be degraded, the surfaces of the reparation body and the bone screws have controllable degradation rate and excellent biological activity and compatibility. The biological degradable magnesium alloy reparation body and the bone screw of the invention can be used in skull wound and reshape and restoration of human body or animals.

Description

technical field [0001] The invention relates to a medical device, in particular to a biodegradable magnesium alloy prosthetic body and a bone screw for cranial trauma and plastic repair. Background technique [0002] The skull is one of the most important parts of the human skeleton. It protects and supports the brain receptors, forms the cranial cavity that houses the brain, and supports the cranial surface. Once a skull injury occurs, it will not only affect the appearance, but also bring a sense of insecurity to the patient, and even cause various adverse consequences such as skull defect syndrome and brain atrophy. [0003] Cranial defect repair technology has been greatly developed in both basic research and clinical practice, but so far, there is no ideal repair material that not only has excellent mechanical properties and biological compatibility, but also can guide The defective skull regenerates, heals, and can be completely degraded or absorbed by itself, so as t...

Claims

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Application Information

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IPC IPC(8): A61B17/68A61B17/56A61F2/28A61L27/00
Inventor 任伊宾杨柯张炳春肖克沈杨慧宾郑丰
Owner INST OF METAL RESEARCH - CHINESE ACAD OF SCI
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