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Production technique of immunoglobulin compounding agent capable of preventing and treating poultry respiratory disease

An immunoglobulin and respiratory tract technology, applied to the prevention and treatment of poultry respiratory tract diseases, compound preparations, and the prevention and treatment of animal respiratory tract diseases, can solve problems such as not widely used, and achieve high infection rate, high price, and rapid disease spread. Effect

Inactive Publication Date: 2009-03-25
方希修 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some biological products can enhance the immune function of animals, but they are not widely used at present

Method used

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  • Production technique of immunoglobulin compounding agent capable of preventing and treating poultry respiratory disease

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Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0052] Raw materials: Chinese herbal medicine extracts such as Yemachai, egg yolk immunoglobulin, carrier

[0053] 1. Preparation of Chinese herbal medicine extracts such as Yemazhui:

[0054] According to the ratio of 10 to 1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1:1, using micro The pulverizer is pulverized and mixed, and then the active ingredients are extracted by ultrasonic waves. The soaking time before extraction is 60-90 minutes. The ultrasonic frequency is 20-40kHz, and the ultrasonic treatment is 30min. After filtration, it is made into powder by low-temperature freeze dryer or spray drying.

[0055] 2. Preparation of egg yolk immunoglobulin:

[0056] 2.1 Egg immunization preparation: select healthy laying hens, and use commercial or self-made multivalent vaccines for respiratory pathogenic microorganisms (such a...

specific Embodiment approach 2

[0065] Raw materials: extracts of Chinese herbal medicines such as Yemachai, egg yolk, carrier

[0066] 1. Preparation of Chinese herbal medicine extracts such as Yemazhui: according to the Chinese herbal medicines such as Yemazhui, Banlangen, Ephedra, Campanulaceae, Andrographis paniculata, Houttuynia cordata, Astragalus, Tinglizi, Poria 10~1:1:1:1:1:1:1 : Mixed at a ratio of 1:1, pulverized with a micro pulverizer and mixed, and then extracted with ultrasonic waves to extract the active ingredients. The soaking time before extraction is 60-90 minutes. The ultrasonic frequency is 20-40kHz, and the ultrasonic treatment is 30min. After filtration, it is made into powder by low-temperature freeze dryer or spray drying.

[0067] 2. Egg yolk preparation:

[0068] After the fresh high-free eggs are sterilized, beat the eggs manually to get the yolk or get the egg yolk liquid through the egg white / yolk separator.

[0069] 3. Preparation of Chinese herbal medicine and egg yolk com...

specific Embodiment approach 3

[0071] Raw materials: Chinese herbal medicine extract, egg yolk egg white, carrier

[0072] 1.1. Yemazhui and other Chinese herbal medicine extract preparation: according to Yemazhui, Banlangen, Ephedra, Campanulaceae, Andrographis paniculata, Houttuynia cordata, Astragalus, Tinglizi, Poria and other Chinese herbal medicines 10~1:1:1:1:1:1:1 : Mixed at a ratio of 1:1, pulverized by a micro pulverizer and then mixed, and then extracted with ultrasonic waves to extract the active ingredients. The soaking time before extraction is 60-90 minutes. The ultrasonic frequency is 20-40kHz, and the ultrasonic treatment is 30min. After filtration, it is made into powder by low-temperature freeze dryer or spray drying.

[0073] 2. Preparation of egg yolk and egg white:

[0074] After the fresh high-free eggs are sterilized, beat the eggs to get the yolk and egg white, remove the egg shell or get the egg yolk liquid through the egg white / egg yolk separator.

[0075] 3. Preparation of Chi...

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Abstract

The invention relates to the field of veterinary drug and feed additive, in particular to a manufacturing method of immunoglobulin composite preparation specially preventing and curing respiratory diseases of fowl. The invention is characterized in that the immunoglobulin composite preparation is made by mixing specificity immunoglobulin or non-extractive containing the specificity immunoglobulin adding with part of carrier or filling material and the like according to certain mixture ratio. The invention integrates the advantages of immunoglobulin and the carrier or the filling material to form a novel substitute of antibiotic so as to achieve the purpose for treating both principal and secondary aspect of disease, fastening the recovery of respiratory diseases of the fowl and preventing and curing the disease, simultaneously reduces the cost, is a safe and non-hormonal green product, has special good effect for the respiratory diseases of the fowl, achieves the cure rate of more than 98 percent and improves the growth speed of the fowl by more than 8 percent. The invention is especially suitable for prevention and treatment of the respiratory diseases of the fowl, various livestock and pets, and the like.

Description

(1) Technical field [0001] The invention relates to the field of veterinary medicine and feed additives, in particular to a production method of a compound preparation of immunoglobulin, wild horse chasing and the like, which can effectively prevent and treat poultry respiratory diseases. [0002] The invention is particularly suitable for the prevention and treatment of poultry respiratory diseases, and is also suitable for the prevention and treatment of animal respiratory diseases such as various livestock and pets. (2) Background technology [0003] Poultry upper respiratory tract infection refers to the disease caused by the invasion of pathogenic microorganisms in the upper respiratory tract of poultry. Common respiratory diseases in poultry (take chickens as an example) are mainly caused by viruses, bacteria and Mycoplasma septicemia, etc. The main clinical features are tearing, runny nose, cough, wheezing, rales, dyspnea, and eye swelling. Infectious laryngotracheit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/395A61P11/00A61P31/14A61K36/78
Inventor 方希修王寿轩王冬梅
Owner 方希修
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