Cefdinir dry suspension agent

A dry suspension, cefdinir technology, applied in the field of cefdinir dry suspension, can solve the problems of less competition in the same variety, and achieve the effects of good stability, high quality and simple method

Inactive Publication Date: 2009-07-01
BEIJING HOPE HUGE PHARM SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0017] 4. There are few domestic manufacturers. At present, only Tianjin Central Pharmaceutical Co., Ltd. and Japan Fujisawa Pharmac...

Method used

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  • Cefdinir dry suspension agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: specification 1000 bags

[0036] prescription:

[0037] Cefdinir 50g

[0038] Sucrose 100g

[0039] Lactose 200g

[0040] Mannitol 150g

[0041] Dextrin 450g

[0042] Xanthan gum 2g

[0043] Sodium carboxymethyl starch 10g

[0044] Aspartame 0.32g

[0045] Strawberry essence 4.8g

[0046] 60% ethanol appropriate amount

[0047] Preparation method:

[0048] Pass cefdinir, dextrin, sucrose, lactose, mannitol, sodium carboxymethyl starch, and xanthan gum through a 100-mesh sieve, mix and stir for 30 minutes, add the prescribed amount of aspartame and strawberry essence to 60% ethanol It can be dissolved to make adhesive and make soft material. Granulate with a 30-mesh sieve, dry at 55-60°C, and granulate with a 30-mesh sieve.

Embodiment 2

[0049] Embodiment 2: specification 10000 bags

[0050] prescription:

[0051] Cefdinir 500g

[0052]Sucrose 1000g

[0053] Lactose 2000g

[0054] Mannitol 1500g

[0055] Dextrin 4500g

[0056] Xanthan gum 20g

[0057] Sodium carboxymethyl starch 100g

[0058] Aspartame 3.2g

[0059] Strawberry essence 48g

[0060] 60% ethanol appropriate amount

[0061] Preparation method:

[0062] Pass cefdinir, dextrin, sucrose, lactose, mannitol, sodium carboxymethyl starch, and xanthan gum through a 100-mesh sieve, mix and stir for 30 minutes, add the prescribed amount of aspartame and strawberry essence to 60% ethanol It can be dissolved to make adhesive and make soft material. Granulate with a 30-mesh sieve, dry at 55-60°C, and granulate with a 30-mesh sieve.

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PUM

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Abstract

The invention belongs to the novel technical field of medicament, specifically relates to cefdinir dry suspension applied to the treatment of inflection caused by staphylococcus, streptocoaus, propionibacterium, gonococcus, colibacillus, Klebsiella pneumoniae, proteus mirabilis, hemophilus influenzae, and Providence bacteria such as pharyngolaryngitis, tonsillitis , bronchitis, pneumonia, pyelonephritis, cystitis and gynaecologic, surgical, dermal, and soft tissue infection.

Description

technical field [0001] The invention belongs to the field of new medicine technology and relates to a new dosage form of cefdinir, which is used for treating Staphylococcus, Streptococcus, Propionibacterium, Neisseria gonorrhoeae, Escherichia coli, Klebsiella, Proteus mirabilis, Influenza bacillus, Common Infections caused by Ruwitense bacteria, such as pharyngitis, tonsillitis, bronchitis, pneumonia, pyelonephritis, cystitis, gonococcal urethritis, gynecology, surgery, skin, soft tissue infection, etc. Specifically, it is a cefdinir dry suspension. Background technique [0002] Since cephalosporins entered the Chinese market in the 1970s, they have been widely used clinically due to their strong antibacterial effect, high clinical curative effect, low toxicity, and less allergic reactions, and their sales have gradually increased to more than 50% of the total amount of anti-infective drugs. However, after years of clinical use, bacteria have generally developed resistance ...

Claims

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Application Information

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IPC IPC(8): A61K31/546A61K9/16A61K47/36A61P31/04A61P11/00A61P13/00A61P15/00A61P17/02
CPCY02A50/30
Inventor 王翰斌闫艳立吴广俣
Owner BEIJING HOPE HUGE PHARM SCI
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