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Method for extracting lentinan from foot of lentinus edodes

A technology of lentinan and lentinan, which is applied in the field of pharmaceutical processing and extraction of lentinan, can solve the problems of high energy consumption, high production cost, and low extraction rate, and achieve the effects of reduced production cost, less equipment investment, and simple process routes

Inactive Publication Date: 2009-10-14
何颖娜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional method of extracting lentinan from shiitake mushrooms or shiitake stalks is water extraction and alcohol precipitation method. Although the process is simple, the extraction rate is not high, and the extraction rate of lentinan is only 4%.
In addition, using hot water extraction (80-100°C) to extract energy consumes a lot and the production cost is high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: get 100kg mushroom stalks, dry to its moisture content 3%, cross 40 mesh sieves after pulverizing, then soak the mushroom stalk powder in concentration and be 70% ethanol solution for 5 hours and carry out degreasing treatment, the consumption of ethanol is 1500kg, defatted shiitake stalk powder, suction filtered, and dried to a moisture content of 3%; the above pretreated degreased shiitake stalk powder was subjected to heat reflux extraction at a temperature of 60°C, and the extraction solution was 0.4mol / L dilute acetic acid Solution, the amount of dilute acetic acid solution during extraction is 5000kg, the extraction time is 90 minutes, and the pressure used is 2.5MPa; the above extraction solution is concentrated in a vacuum, and the extraction solution is concentrated to 1 / 2 of the original volume to obtain Lentinan Rough extraction concentrated solution: add 95% ethanol to the above-mentioned lentinan crude extraction concentrated solution, the volu...

Embodiment 2

[0015] Embodiment 2: get 100kg shiitake mushroom stalks, dry to its moisture content 5%, cross 60 mesh sieves after pulverizing, then the shiitake mushroom stalk powder is soaked in the ethanol solution of 90% concentration to carry out degreasing treatment for 2 hours, and the consumption of ethanol is 1000kg, defatted shiitake stalk powder, suction-filtered, and dried until its moisture content was 5%; the pretreated degreased shiitake stalk powder was leached under hot reflux at 70°C, and the leaching solution was 0.1mol / L dilute hydrochloric acid Solution, the amount of dilute hydrochloric acid solution during extraction is 3000kg, the extraction time is 60 minutes, and the pressure used is 6MPa; the above extraction solution is concentrated by ultrafiltration, and the extraction solution is concentrated to 1 / 3 of the original volume to obtain Lentinan Rough extraction concentrated solution; add 95% ethanol to the above-mentioned lentinan crude extraction concentrated solut...

Embodiment 3

[0016] Embodiment 3: get 100kg mushroom stalk, dry to its moisture content 4%, cross 50 mesh sieves after pulverizing, then soak the mushroom stalk powder in concentration and be 80% ethanol solution and carry out degreasing treatment for 3 hours, the consumption of ethanol is 1200kg, the shiitake stalk powder is degreased, then suction-filtered, and dried until its moisture content is 4%; the above-mentioned pretreated defatted shiitake stalk powder is subjected to heat reflux extraction at a temperature of 50°C, and the extraction solution is 0.2mol / L dilute hydrochloric acid solution, the amount of dilute hydrochloric acid solution during leaching is 4000kg, the leaching time is 70 minutes, and the pressure used is 12.5MPa; the above-mentioned leaching solution is concentrated by distillation under reduced pressure (pressure 0.09MPa, temperature 40 ℃), and the leaching solution is concentrated to 1 / 5 of the original volume to obtain the lentinan crude extract concentrate; ad...

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Abstract

A method for extracting lentinan from the foot of lentinus edodes belongs to the technical field of polyose and derivatives processing and is used for solving the problem of improving the extraction rate of lentinan in the foot of lentinus edodes. The technical proposal is as follows: the foot of lentinus edodes is taken as raw material to prepare the lentinan through the steps of pretreatment, extraction, concentration, alcohol sedimentation and separation, drying and the like. After improvement, the extraction step is as follows: pretreated degreased lentinus edodes foot powder is extracted under decompressed hot reflux at the temperature of 40-70 DEG C; leaching liquor is 0.1-0.4mol / L diluted acid solution; the mass ratio of the diluted acid solution and the lentinus edodes foot powder is 30-50:1 when leaching; the leaching time is 40-90min; the pressure adopted in leaching is 2.5-15MPa; and the diluted acid solution is volatile acid solutions of hydrochloric acid, acetic acid and the like. The method increases the rate of extracting the lentinan from the foot of the lentinus edodes to a great degree, effectively improves the utilization rate of the raw material, reduces production cost, has simple and direct process route and little equipment investment, and is easy for industrialization and an effective method for comprehensively processing and using the foot of the lentinus edodes.

Description

technical field [0001] The invention relates to a medicine processing method, in particular to a method for extracting lentinan from shiitake stalks, belonging to the technical field of polysaccharide and derivative processing. Background technique [0002] Modern medical research believes that shiitake mushrooms have various pharmacological effects and biological activities. The water-soluble component lentinan extracted from shiitake mushrooms is the main functional component of the biological effects of shiitake mushrooms. and immune regulation. The stipe of shiitake mushrooms is medium to partial, white, solid inside, and has a semi-flesh to fibrous structure. Its taste and taste are slightly inferior to those of the caps of shiitake mushrooms. As a by-product in the processing of shiitake mushrooms, during the initial processing of shiitake mushrooms, Usually the stalk of the shiitake is removed from the fruiting body of the shiitake. Studies have confirmed that the s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B37/00
Inventor 何颖娜
Owner 何颖娜
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