Trimethylglyine compound nanoemulsion used for nourishing and moisturizing skin and preparation method thereof

A technology of trimethylglycine lactone and trimethylglycine, applied in the field of trimethylglycine lactone composite nanoemulsion and its preparation, to achieve the effects of easy transdermal absorption, uniform distribution, and stable products

Inactive Publication Date: 2010-03-10
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there are also shortcomings in the actual application of nanoemulsions: emulsifiers and co-emulsifiers are essential components for the formation of nanoemulsions, and they have certain irritation and toxicity. How to reduce the amount of emulsifiers and co-emulsifiers; How to determine the best matching emulsifier and co-emulsifier, how to determine the formulation and preparation process of the best trimethylglycine lactone moisturizing effect nanoemulsion; how to make the functional ingredients in the trimethylglycine lactone moisturizing effect nanoemulsion play a role Better moisturizing effect and advantages; how to select and determine the type and application dosage or concentration of functional ingredients in trimethylglycinolactone moisturizing effect nanoemulsion, etc. are unresolved problems

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  • Trimethylglyine compound nanoemulsion used for nourishing and moisturizing skin and preparation method thereof

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Embodiment Construction

[0085] The optimal weight ratio of each raw material is: isopropyl myristate 12.86, caprylic capric acid macrogol glyceride 31.5, polyglycerol fatty acid ester 10.5, triple distilled water 35.42, citric acid 0.05, trisodium citrate dihydrate 0.99 , trimethyl glycine lactone 1.77, hydroxyethyl carboxamide 1.77, vitamin E3.86, azone 1.29.

[0086] The preparation method of trimethylglycine moisturizing nanoemulsion for external use on the skin (take the preparation of 1000g as an example): ① use an analytical balance to accurately weigh 0.5g of citric acid and 9.9g of trisodium citrate dihydrate and place them in a decontaminated 1000mL In the Erlenmeyer flask, add 354.2g of triple distilled water to fully dissolve, then add 17.7g of trimethylglycine lactone and 17.7g of ethyl carboxamide, ultrasonically shake and dissolve, and clearly mark it as the water phase with a colored marker (1) 400g, and this solution is used as the water phase. ②Use an analytical balance to accuratel...

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Abstract

The invention relates to a trimethylglyine compound nanoemulsion used for nourishing and moisturizing skin and a preparation method thereof. The nanoemulsion is prepared from the following raw materials in parts by weight: 10-17 parts of isopropyl myristate, 20-25 parts of Caprylocaproyl Macrogolglycerides, 6-16 parts of polyglyceryl fatty acid ester, 33-38 parts of triple distilled water, 0.1-1.0part of citric acid, 5.5-12 parts of Trisodium citrate dihydrate, 13-19 parts of trimethylglyine lactone, 13-19 parts of hydroxyethyl carbomite, 36-46 parts of Vitamin E and 10-16 parts of azone. Theinvention has the innovations that the newest international drug targeting vector transfer system is improved and optimized so as to enable the nanoemulsion to have dual effects of nourishing and moisturizing skin; the nanoemulsion can be made up and produced only at normal temperature, and the complex processes of respectively dissolving, heating, then mixing and emulsifying the oil phase and the water phase are not needed; the process is scientific, the operation is simple, special equipment is not needed, the preparation period is short (about 30 min), the production efficiency is high, and the industrialization is easy to realize; moreover, the nanoemulsion has stable quality, high comfort and high safety, and the effect ingredients are not easy to break; compared with the like products, the nanoemulsion has better effect, saves more energy, energy resources, materials, time and cost, reduces environmental pollution and the like.

Description

technical field [0001] The invention relates to a new type of beauty care cosmetic product and its preparation technology that can be directly applied to skin nutrition and moisturizing after the improved and optimized drug targeting carrier preparation technology, in particular to a trimethylglycine internal medicine that can be used for skin nutrition and moisturizing dual functions. Ester composite nanoemulsion and its preparation method. Background technique [0002] With the advancement of science and technology and the improvement of people's living standards, people have higher and higher functional requirements for beauty cosmetics, not only for skin color, but also for skin quality. Skin moisturizing is the basis for skin texture, luster, smoothness, and skin prevention. Or the most important indicator of anti-aging. Therefore, the skin moisturizing function has become one of the subjects of beauty cosmetics research and development, which has attracted much attent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/49A61K8/85A61K8/06A61Q19/00
Inventor 杨永鹏朱晓亮董萍丁宇丁克祥
Owner 董萍
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