1 results about "Citrinin hydrate" patented technology

This invention relates to the field of nanomaterial dispersion technology, and discloses a nano-hydroxyapatite suspension and its preparation method, comprising nano-hydroxyapatite, thixotropic nanoparticles, N,O-carboxymethyl chitosan, one or two of glycerol and D-sorbitol, poloxamer 407, trisodium citrate dihydrate, xylitol, sodium benzoate, and deionized water. The preparation method includes preparing an A-phase dispersion containing thixotropic nanoparticles and a B-phase suspension containing nano-hydroxyapatite. The B-phase suspension is dropwise added to the A-phase dispersion to react and obtain a three-dimensional composite framework. An auxiliary phase is added for low-shear mixing and vacuum degassing and degassing. This invention constructs a three-dimensional network framework by crosslinking thixotropic nanoparticles with N,O-carboxymethyl chitosan, which hinders the aggregation and gravitational sedimentation of nano-hydroxyapatite particles, giving the system thixotropic properties that are stable at rest and flow under stress, achieving framework dissociation and particle release under slightly acidic conditions.