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Ginkgo leaf-containing chewable tablet and preparation method thereof

A technology of Ginkgo biloba leaves and chewable tablets is applied in the directions of medical raw materials derived from Ginkgo biloba, non-active components of polymer compounds, and pill delivery, etc. Reports and other issues to avoid side effects, rich sources, and control the occurrence of diabetes complications and inflammation

Inactive Publication Date: 2010-06-30
天津金世制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A Japanese company made ginkgo leaves into teabags for sale, and conducted feedback surveys on drinkers. The results showed that the product can improve diabetes symptoms and enhance physical fitness, but it tends to have a bitter taste when drinking, and the taste is not very good
In particular, the ginkgo biloba chewable tablets made from a single component of ginkgo biloba and pure xylose have not been reported in the literature

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Take 50 grams of dried clean ginkgo leaves, decoct in 600ml of water for 3 hours, decoct in 500ml of water for 2 hours, decoct in 500ml of water for 2 hours, concentrate to a specific gravity of 1.2, and centrifuge at high speed; the supernatant is passed through a macroporous resin such as AB- Type 8 resin, eluted with water until there is no polysaccharide component, concentrated eluent, precipitated with 85% alcohol, filtered, vacuum dried, crushed and sieved or spray dried to obtain 11 grams of yellow fine powder extract for future use.

Embodiment 2

[0026] 11 grams of fine powdered Ginkgo biloba extract, 10 grams of xylitol, 100 grams of sorbitol, 40 grams of citric acid, 5 grams of aspartame, 350 grams of starch, 80 grams of dextrin, 10 grams of magnesium stearate, prepared into 220 tablets.

Embodiment 3

[0028] 10 grams of fine powdered Ginkgo biloba extract, 18 grams of xylitol, 18 grams of sorbitol, 0.9 grams of citric acid, 0.5 grams of aspartame, 57.6 grams of starch, 14.4 grams of dextrin, and 1.5 grams of magnesium stearate. into 100 tablets.

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PUM

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Abstract

The invention discloses ginkgo leaf-containing chewable tablet and preparation method thereof, which is characterized in that the ginkgo leaf-containing chewable tablet includes the following materials, by weight, 1-10 powder extract, 10-80 medical auxiliary material and 1-30 xylitol, wherein the powder extract is ginkgo leaf powder extract which contains no less than 85% of total flavone and is prepared as follows: decocting dry and clean ginkgo leaves, concentrating, high speed centrifugation, adsorbing the centrifugate through resin, eluting through 85% ethanol, alcohol precipitating, dehydrating, vacuum drying, grinding, sieving and spray drying. The ginkgo leaf-containing chewable tablet is capable of effectively controlling the rise of blood sugar without insulin metabolism, thereby providing good clinical drug for diabetics.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a chewable tablet containing ginkgo leaves and a preparation method thereof. Background technique [0002] Inflammation is a complex process, which is a defense response of a living body with a vascular system to an injury factor. Moderate inflammatory response is an immune response for the body to protect itself. Excessive inflammation can lead to immune damage of the body and cause various diseases. Many anti-inflammatory drugs have been developed, but their efficacy against those allergic severe inflammations is still unsatisfactory. Therefore, it is increasingly important to develop effective anti-inflammatory drugs. Cell adhesion is an important physiological phenomenon of the body, and the adhesion of leukocytes and vascular endothelial cells plays an important role in maintaining the normal activities of the body, mediating inflammation,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A61K9/20A61K47/40A61P3/10A61K127/00
Inventor 宋富智
Owner 天津金世制药有限公司
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