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Echinacea purpurea extract powder and preparation method and application thereof

A technology of Echinacea purpurea extract and Echinacea purpurea, which is applied in the directions of pharmaceutical formulations, antiviral agents, drug combinations, etc., can solve the problems of large dosage of powder, waste of drug resources, low bioavailability, etc., and achieves fast dissolution speed and easy storage. And the effect of using and extracting high efficiency

Active Publication Date: 2011-09-07
QINGDAO VLAND BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention provides a powder of echinacea purpurea extract and its preparation method and application, which can solve the problems of large dosage, slow onset of action, low bioavailability, easy moisture absorption and caking, and serious waste of drug resources. The problem

Method used

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  • Echinacea purpurea extract powder and preparation method and application thereof
  • Echinacea purpurea extract powder and preparation method and application thereof
  • Echinacea purpurea extract powder and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] A preparation method of Echinacea purpurea extract powder, the steps are as follows:

[0051] (1) Pulverize the Chinese-introduced Echinacea purpurea with a water content of ≤12% with a plant grinder, and pass through a 80-mesh sieve to obtain Echinacea purpurea coarse powder;

[0052] (2) Weigh 1000g of the Echinacea purpurea powder obtained in step (1) into a microwave extractor, add 70% ethanol solution according to the ratio of solid-liquid ratio (Kg:L) 1:10, soak for 30 minutes, and microwave extract 2 times, microwave frequency: 2400-2500MHz, extraction temperature: 70°C, extraction time: 10 minutes, filter, recover ethanol from the filtrate, concentrate under reduced pressure to obtain the extract of Echinacea purpurea extract;

[0053] (3) Microwave the dregs obtained by filtering in step (2) twice with 20% ethanol solution, solid-liquid ratio (Kg:L) 1:10, microwave frequency: 2400-2500MHz, extraction temperature: 70°C, extract Time: 10 minutes, filter, and rec...

Embodiment 2

[0057] (1) Pulverize the Chinese-introduced Echinacea purpurea with a water content of ≤12% with a plant grinder, and pass through a 80-mesh sieve to obtain Echinacea purpurea coarse powder;

[0058] (2) Weigh 2000g of the Echinacea purpurea powder obtained in step (1) into a microwave extractor, add 60% ethanol solution according to the ratio of solid-liquid ratio (Kg:L) 1:8, soak for 30 minutes, and microwave extract 2 times, microwave frequency: 2400-2500MHz, extraction temperature: 80°C, extraction time: 15 minutes, filter, recover ethanol from the filtrate, concentrate under reduced pressure to obtain the extract of Echinacea purpurea extract;

[0059] (3) Extract the dregs obtained by filtering in step (2) twice with 20-30% ethanol solution microwave, solid-liquid ratio (Kg:L) 1:10, microwave frequency: 2400-2500MHz, extraction temperature: 80 ℃, extraction time: 5 minutes, filter, recover ethanol from the filtrate to obtain the extract of Echinacea purpurea extract;

...

Embodiment 3

[0063] Clinical trial of the obtained Echinacea purpurea extract powder of embodiment 1

[0064] grouping and processing

[0065] Sixty 21-day-old weaned triple hybrid piglets were randomly divided into 3 groups. The diet of the Echinacea purpurea group was supplemented with 0.5% Echinacea purpurea extract powder, the drug control group was supplemented with 0.02% colistin sulfate, and the control group was fed the basic diet. 7, 14 and 28 days after the addition, blood was collected from 5 heads in each group, and the transformation activity of peripheral blood lymphocytes and the contents of serum immunoglobulin and cytokines were determined.

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Abstract

The invention provides echinacea purpurea extract powder and a preparation method and application thereof, which can solve the problems of large dosage, slow response, low bioavailability, easy moisture absorption and agglomeration and serious waste of medicament resources of the powder which is prepared by a traditional preparation method. The echinacea purpurea extract powder comprises echinacea purpurea extract and micro-powder silica gel serving as a carrier material. The preparation method comprises the steps of crushing the raw medicament material echinacea purpurea, extracting the material by a microwave method, recovering ethanol, performing concentration on the material under reduced pressure, adsorbing the micro-powder silica gel and drying, compounding and packaging the material. The echinacea purpurea extract powder has high dissolution rate and high dissolution capability of the effective ingredient, ensures convenient storage and use of the echinacea purpurea superfine powder by adding the micro-powder silica gel serving as a moisture remover, an anti-caking agent and a flow aid and has a good effect for enhancing the immune function; and the echinacea purpurea extract powder is used for animals of low immune function and improving the immunity effect of vaccine so as to cure various bacterial diseases and viral diseases by matching with other medicaments.

Description

technical field [0001] The invention belongs to the field of veterinary natural medicine preparations, and in particular relates to a powder of echinacea purpurea extract and its preparation method and application. Background technique [0002] The immune and preventive function of the animal body and the immune system of the animal body directly affect the production performance of the animal. Maintaining the normal immune and preventive function of the animal body is the prerequisite for making the animal reach the normal production level or exert the potential best production performance. The research progress of immune enhancers is also a process of mutual integration and promotion of immunobiology, immunopharmacology of traditional Chinese medicine, microbiology, molecular biology, animal nutrition, animal production and human health, which represents the development trend of drug development. The industry no longer takes into account the rewards brought by the existenc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61K47/04A61K9/14A61P37/04A61P31/04A61P31/12A61K135/00A61K127/00A61K133/00
Inventor 郝智慧王春元贾德强王艳玲庞云露
Owner QINGDAO VLAND BIOTECH INC
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