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Vitamin water aqua and preparation method thereof

A technology of vitamins and fat-soluble vitamins, applied in the directions of pharmaceutical formulas, additional food elements, and medical preparations containing active ingredients, etc., can solve the problems of few active ingredients, unstable process and complexity of water preparations, etc., to enhance disease resistance. , to avoid loss and insufficient utilization, the effect of stable storage properties

Active Publication Date: 2010-09-08
DINGZHENG XINXING BIOTECH TIANJIN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently known methods have the disadvantages of less effective ingredients in the water preparation, instability of the water preparation and complex processes

Method used

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  • Vitamin water aqua and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A kind of preparation method of vitamin water preparation comprises the following steps:

[0031] (1) Preparation of liposomes

[0032] Mix 10g of soybean lecithin and 5g of cholesterol and add to the reaction kettle, the reaction time is 30-45min, and the reaction temperature is 20°C;

[0033] (2) Preparation of fat-soluble vitamin solution

[0034] Dissolve 11000000IU (3.78g) vitamin A, 160000000IU (4g) vitamin D, 2000IU (2g) vitamin E, 1000IU (1g) vitamin K, 10g polyethylene glycol 6000 and 5g polyvinylpyrrolidone in the organic solvent chloroform and ethanol (The weight ratio of chloroform and ethanol is 2: 1) in the mixed solution, makes fat-soluble vitamin solution;

[0035] (3) Preparation of water-soluble vitamin solution

[0036] Dissolve 4g of vitamin B1, 4g of vitamin B2, 2g of vitamin B6, 2g of vitamin B12, 4g of vitamin C, 2g of vitamin H, and 2g of folic acid in PBS buffer with a pH value of 6.0, and the temperature of the buffer is 30°C to obtain a wat...

Embodiment 2

[0043] A kind of preparation method of vitamin water preparation comprises the following steps:

[0044] (1) Preparation of liposomes

[0045] Mix 10g of soybean lecithin, 20g of sorbitol and 5g of cholesterol into the reactor, the reaction time is 3045min, and the reaction temperature is 65°C;

[0046] (2) Preparation of fat-soluble vitamin solution

[0047] Dissolve 5500000IU (1.89g) vitamin A, 160000000IU (4g) vitamin D, 2000IU (2g) vitamin E, 1000IU (1g) vitamin K, 10g polyethylene glycol 6000 and 5g polyvinylpyrrolidone in the organic solvent chloroform and ethanol (The weight ratio of chloroform and ethanol is 2: 1) in the mixed solution, makes fat-soluble vitamin solution;

[0048] (3) Preparation of water-soluble vitamin solution

[0049] Dissolve 4g of vitamin B1, 2g of vitamin B2, 2g of vitamin B6, 1g of vitamin B12, 6g of vitamin C, 2g of vitamin H, and 2g of folic acid in PBS buffer with a pH value of 7.4, and the temperature of the buffer is 45°C to obtain a wa...

Embodiment 3

[0056] A kind of preparation method of vitamin water preparation comprises the following steps:

[0057] (1) Preparation of liposomes

[0058] Mix 5g of soybean lecithin, 5g of distearoylphosphatidylcholine, 20g of sorbitol and 5g of cholesterol and add them into the reaction kettle. The reaction time is 30-45min, and the reaction temperature is 55°C;

[0059] (2) Preparation of fat-soluble vitamin solution

[0060] Dissolve 11000000IU (3.78g) vitamin A, 160000000IU (4g) vitamin D, 2000IU (2g) vitamin E, 2000IU (2g) vitamin K, 10g polyethylene glycol 6000 and 5g polyvinylpyrrolidone in the organic solvent chloroform and ethanol (The weight ratio of chloroform and ethanol is 2: 1) in the mixed solution, makes fat-soluble vitamin solution;

[0061] (3) Preparation of water-soluble vitamin solution

[0062] Dissolve 4g of vitamin B1, 2g of vitamin B2, 6g of vitamin B6, 2g of vitamin B12, 4g of vitamin C, 2g of vitamin H, and 2g of folic acid in PBS buffer with a pH value of 7.0,...

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Abstract

The invention relates to a vitamin water aqua. The raw materials of the water aqua comprise liposome, vitamin A, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin H, folic acid and solubilizer. In the invention, liposoluble vitamins are coated in a microcapsule structure of the liposome and form a homogenized and stable water aqua with water-soluble vitamins. The water aqua has stable storage character in a long time, smaller grain diameter of components and a cytoid structure and can activate the self immunologic function after entering an animal body to keep the immune level of organisms in a higher state; and meanwhile, a plurality of vitamins can be effectively stored in the organism, so that the invention avoids the problems of the loss and the insufficient utilization rate of the vitamins in the metabolic process, remarkably improves the utilization rate and the conversion rate of feed, improves the antibody level of animal organisms and enhances the disease resistant capability.

Description

technical field [0001] The invention belongs to a vitamin additive in animal aquaculture technology, in particular to a vitamin water preparation and a preparation method thereof. Background technique [0002] Vitamin is an organic substance necessary for the body to maintain normal functions, but it cannot be synthesized in the body, or the amount of synthesis is very small, and it needs to be ingested through food. Vitamins play an important role in regulating the body's substance metabolism and maintaining physiological functions. It mainly participates in various chemical reactions in the body's metabolism in the form of coenzymes and catalysts, so as to ensure the normal cell structure and function of the body's tissues and organs. To maintain the normal daily health and various activities of animals, the lack of vitamins can cause metabolic disorders in the body, affecting animal health and normal biological activities. [0003] Vitamins can be divided into fat-solubl...

Claims

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Application Information

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IPC IPC(8): A23K1/16
CPCA61K9/127A23K1/164A23D7/011A23K1/1603A23D9/013A61K31/51A61K31/714A23K20/158A23K20/174A61P3/02
Inventor 刘鼎阔王立红董惠峰张勇张凤洪张俊霞
Owner DINGZHENG XINXING BIOTECH TIANJIN
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