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Nanometer taxus chinensis powder and preparation method thereof

A yew, nano crushing technology, applied in the direction of powder delivery, medical raw materials derived from gymnosperm subphylum, drug combination, etc., to reduce the difficulty of extraction, reduce the price, and facilitate the effect of oral or injection

Inactive Publication Date: 2010-09-22
粟时献
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many kinds of yew products and their production methods at home and abroad, but nano-yew powder and its production methods are still the first

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0008] The specific implementation method of the present invention is divided into three steps: the first step, utilize pulverizer to pulverize yew, make the average particle diameter of its powder particle reach 50~200 orders; The yew is crushed so that the average particle size of the powder particles reaches 2000-8000 mesh; the third step is to use a nano-pulverizer to crush the yew after airflow crushing so that the average particle size of the powder particles reaches 1-1000 nanometers (The detection of its particle size can be identified by scanning electron microscope, transmission electron microscope, laser particle size analyzer or X-ray small angle scattering method).

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PUM

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Abstract

The invention provides a nanometer taxus chinensis product and a preparation method thereof. In the method, the taxus chinensis is taken as a raw material, the latest nano process technology and pure physical method are utilized and the taxus chinensis is crushed into powder through mechanical forces, wherein the average grain diameter of the powder particle is 1-1000 nanometer, thus the cellwall of the taxus chinensis is completely broken, the various components in the taxus chinensis are completely released, the permeability is improved greatly, and the effect and the curative effect are both improved substantially. The invention makes full use of the root, stem, leaves, trunk and bark of the taxus chinensis, is close to zero wastage of raw materials during process, and can greatly save the taxus chinensis resources.

Description

technical field [0001] The invention belongs to the technical field of ultrafine pulverization and relates to a yew product and a manufacturing method thereof. Background technique [0002] Yew (basically evergreen shrubs or trees of Taxaceae) is a rare and natural anti-cancer plant that is recognized worldwide as being on the verge of extinction. It is a first-class protected plant in my country and a rare and endangered plant in the world. Taxus is very precious because it contains paclitaxel, a special anticancer drug. Paclitaxel is the best anticancer drug in the world after adriamycin and cisplatin. It is effective for advanced breast cancer, ovarian cancer, uterine cancer, esophageal cancer, Nasopharyngeal cancer, upper gastrointestinal cancer, bladder cancer, lymphoma, prostate cancer, malignant melanoma, head and neck cancer, small cell and non-small cell lung cancer all have significant curative effects, known as "advanced cancer patients last line of defense". Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/13A61K9/14A61P35/00A61K135/00A61K129/00A61K127/00A61K125/00
Inventor 粟时献
Owner 粟时献
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