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Method for preparing bacterial cellulose hydrogel temperature-reducing plaster and product thereof

A technology of bacterial cellulose and hydrogel, which is applied in the directions of microorganism-based methods, biochemical equipment and methods, and non-active ingredients medical preparations, etc. Control, low cost, good air permeability

Inactive Publication Date: 2010-11-10
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation process route is more complicated and the cost is higher

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] (1) The bacterial cellulose hydrogel membrane was prepared by Acetobacter xylinum, and the separated and purified bacterial cellulose hydrogel membrane was partially dehydrated to obtain a bacterial cellulose hydrogel membrane with a water content of 70%.

[0027] (2) The gelatin solution is double-distilled in water to obtain an aqueous gelatin solution in which the mass percentage of gelatin accounts for 2% by mass of the aqueous gelatin solution. The borneol is dissolved in the gelatin aqueous solution to obtain an aqueous solution system in which the borneol accounts for 1% of the gelatin aqueous solution and the gelatin-wrapped borneol.

[0028] (3) Soak the treated bacterial cellulose hydrogel film in an aqueous solution system of gelatin-wrapped borneol at a temperature of 37° C. and a standing time of 5 min. After soaking and washing, the composite membrane is dehydrated naturally, packaged, and gamma-irradiated to obtain bacterial cellulose hydrogel, gelatin un...

Embodiment 2

[0030](1) The bacterial cellulose hydrogel membrane is prepared by Acetobacter acetogenes, and the separated and purified bacterial cellulose hydrogel membrane is partially dehydrated to obtain a bacterial cellulose hydrogel membrane with a water content of 90%.

[0031] (2) The gelatin solution is double-distilled in water to obtain a gelatin aqueous solution in which the gelatin mass accounts for 5% of the gelatin aqueous solution mass percent. The borneol is dissolved in the gelatin aqueous solution to obtain an aqueous solution system in which the borneol mass accounts for 5% of the gelatin aqueous solution mass percent and the gelatin-wrapped borneol.

[0032] (3) Soak the treated bacterial cellulose hydrogel film in an aqueous solution system of gelatin-wrapped borneol at a temperature of 37° C. and a standing time of 5 min. After soaking and washing, the composite membrane is dehydrated naturally, packaged, and gamma-irradiated to obtain bacterial cellulose hydrogel, ge...

Embodiment 3

[0034] (1) The bacterial cellulose hydrogel membrane is prepared by Acetobacter acetibacterium, and the separated and purified bacterial cellulose hydrogel membrane is partially dehydrated to obtain a bacterial cellulose hydrogel membrane with a water content of 80%.

[0035] (2) The gelatin solution is double-distilled in water to obtain an aqueous gelatin solution in which the mass percentage of gelatin accounts for 3% of the aqueous gelatin solution. The borneol is dissolved in the gelatin aqueous solution to obtain a gelatin-wrapped menthol aqueous system in which the mass percentage of menthol accounts for 1% of the gelatin aqueous solution.

[0036] (3) Soak the treated bacterial cellulose hydrogel film in an aqueous solution system of gelatin-wrapped menthol at a temperature of 60° C. and a standing time of 30 min. After soaking and washing, the composite film is dehydrated naturally, packaged, and gamma-irradiated to obtain bacteria fibers composed of bacterial cellulo...

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Abstract

The invention discloses a method for preparing a bacterial cellulose hydrogel temperature-reducing plaster and a product thereof, in particular a method for preparing the repeatedly used bacterial cellulose hydrogel temperature-reducing plaster and the product thereof. The method comprises the following steps of: soaking a treated bacterial cellulose hydrogel film which reaches the medicinal level in aqueous solution of gelatin at a certain concentration, and standing for 5 to 30 minutes; and taking a part of the treated bacterial cellulose for dehydrating, packaging and sterilizing so as to obtain the bacterial cellulose hydrogel temperature-reducing plaster which is compounded by the gelatin and the bacterial cellulose. The preparation method has the characteristics of simple and practicable process, convenient operation, controllable preparation technology, no pollution, and low cost. The obtained bacterial cellulose hydrogel temperature-reducing plaster has the advantages of high biocompatibility with the skin, high moisture content, high water-retaining property, strong roughness, good air permeability, effects of cold compress physical therapy, physical temperature reduction, pain relief and the like, and convenient and safe use.

Description

technical field [0001] The invention relates to a preparation method of a bacterial cellulose hydrogel cooling patch and a product thereof, in particular to a preparation method of a reusable bacterial cellulose hydrogel cooling patch and a product thereof. The invention belongs to the field of medical materials, and specifically relates to a reusable hydrogel cooling patch with bacterial cellulose as a base material and a preparation method thereof. Background technique [0002] Fever is caused by the action of fever activators on the body, which in turn leads to the generation of endogenous pyrogens (EP) that are incorporated into the brain and act on the temperature regulation center, which in turn leads to the release of mediators in the fever center and then changes the set point, eventually causing fever. Whether the fever activator comes from an external heat source outside the body or from the body, it can cause enhanced tissue metabolism, digestive dysfunction, musc...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K31/717A61K31/045A61K47/38A61K47/42C12P19/04A61P29/00C12R1/02C12R1/01C12R1/41C12R1/38
CPCY02A50/30
Inventor 李喆朱冰洁杨敬轩彭锟张泽锐张雯胡伟立陈仕艳王华平
Owner DONGHUA UNIV
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