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Application of cyclo olefin copolymer in preparing biological and chemical container

A cyclic olefin and copolymer technology, which is applied in the application field of cyclic olefin copolymer in the preparation of biological and chemical containers, can solve the problems of high cost, low moisture absorption, ordinary glass cannot be sterilized by high-energy radiation, etc. Light, good chemical resistance

Inactive Publication Date: 2011-01-12
SICHUAN PINGKANG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Disadvantages: Ordinary glass cannot be sterilized by high-energy radiation or ethylene oxide, fragile, heavy, and high in energy consumption
[0008] Disadvantages: complex manufacturing process, high technical difficulty, high cost, and certain hygroscopicity
[0011] Disadvantages: Can not meet the performance of high pressure damp heat sterilization, low moisture absorption, good air (steam) tightness, etc. at the same time

Method used

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  • Application of cyclo olefin copolymer in preparing biological and chemical container
  • Application of cyclo olefin copolymer in preparing biological and chemical container
  • Application of cyclo olefin copolymer in preparing biological and chemical container

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The cyclic olefin copolymer involved in the present invention is a polymer copolymer obtained by copolymerization of bicycloheptene monomer and ethylene monomer under the action of a catalyst, and its general molecular formula is:

[0030]

[0031] In the formula, the value of X is 400-7000; the value of Y is 400-7000.

[0032] When the above-mentioned cyclic olefin copolymer is applied to the preparation of bacterial culture bottles, such as blood or body cavity fluid bacterial culture bottles. The preparation method is as follows: using cyclic olefin copolymer pellets with a bicycloheptene content of more than 75% (wt / %) and a heat distortion temperature ≥ 127°C, injection molding the tube blank into a tube, and then blow molding the tube blank into a bottle.

[0033] Can obtain by experiment, adopt the bacterial culture bottle that cyclic olefin copolymer prepares and the comparative performance parameter of existing bacterial culture bottle as shown in the follow...

Embodiment 2

[0037] The difference between this example and Example 1 is that the above-mentioned cyclic olefin copolymer is applied to the preparation of cell culture flasks, such as culture flasks of human or animal tissue cells, insects, and plant tissue cells. The preparation method is as follows: using cyclic olefin copolymer pellets with a bicycloheptene content of more than 75% (wt / %) and a heat distortion temperature ≥ 127°C, injection molding the tube blank into a tube, and then blow molding the tube blank into a bottle.

[0038] It can be obtained through experiments that the comparative performance parameters of the cell culture flask prepared by adopting the cyclic olefin copolymer and the existing cell culture flask are shown in the following table:

[0039]

[0040] It can be seen from the above table that compared with the existing cell culture flasks, the cell culture flasks prepared by using cyclic olefin copolymers can be sterilized by different methods, the flask body ...

Embodiment 3

[0042] The difference between this example and Example 1 is that the above-mentioned cyclic olefin copolymer is applied to the preparation of pharmaceutical packaging bottles, such as liquid medicine and injection medicine packaging bottles. The preparation method is as follows: using cyclic olefin copolymer pellets with a bicycloheptene content of more than 75% (wt / %) and a heat distortion temperature ≥ 127°C, injection molding the tube blank into a tube, and then blow molding the tube blank into a bottle.

[0043] It can be obtained through experiments that the comparative performance parameters of the pharmaceutical packaging bottle prepared by adopting the cyclic olefin copolymer and the existing pharmaceutical packaging bottle are shown in the following table:

[0044]

[0045] It can be seen from the above table that compared with the existing pharmaceutical packaging bottles, the pharmaceutical packaging bottles prepared by using cyclic olefin copolymers have good air...

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Abstract

The invention discloses application of a cyclo olefin copolymer in preparing a biological and chemical container. When the cyclo olefin copolymer is applied to prepare the biological and chemical container, the prepared biological and chemical container has the following advantages: the glass bottle is resistant to heat and transparent, has high gas barrier property and low moisture absorption, can carry out high temperature moist heat sterilization and has good chemical resistance; and other high polymer materials such as plastic bottles are not easy to break, have light weight and can carry out high-energy ray radiation and sterilization with ethylene oxide.

Description

technical field [0001] The invention relates to the application of a cyclic olefin copolymer in the preparation of biological and chemical containers. Background technique [0002] At present, there are mainly three types of biological and chemical containers prepared at home and abroad: [0003] 1. Glass container: [0004] Advantages: transparent, high temperature resistance, good chemical resistance, can be sterilized by damp heat (steam sterilization), good air (steam) tightness, low moisture absorption. [0005] Disadvantages: Ordinary glass cannot be sterilized by high-energy radiation or ethylene oxide, fragile, heavy, and high in energy consumption. [0006] 2. Multi-layer polymer material bottle: the bottle wall is a sandwich layer structure, the inner and outer wall materials can withstand high temperature, low moisture absorption, and the sandwich layer has good air (steam) tightness. [0007] Advantages: It can be sterilized by moist heat, can be sterilized by...

Claims

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Application Information

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IPC IPC(8): C08F232/08C08F210/02C08L45/00B65D65/38B01L1/00
Inventor 王福良
Owner SICHUAN PINGKANG TECH
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