The invention discloses a method for producing a large-thickness lamination-crack-resistant tempered high-strength steel plate. The method is characterized by comprising the steps: smelting, performing continuous casting, performing electroslag remelting, heating, rolling, annealing and performing heat treatment. The steel plate comprises the following chemical components in percentage by weight: 0.14-0.18 percent of C, 0.20-0.50 percent of Si, 0.95-1.25 percent of Mn, less than or equal to 0.015 percent of P, less than or equal to 0.005 percent of S, 0.80-1.15 percent of Ni, 0.40-0.60 percent of Cr, 0.40-0.60 percent of Mo, 0.020-0.050 percent of Nb, 0.010-0.030 percent of Ti, 0.020-0.045 percent of TAl, and the balance of Fe and inevitable impurities. According to the method, electroslag remelting treatment is adopted, good overall performance of the large-thickness steel plate with the diameter of 30mm can be met due to the reasonable controlled rolling and heat treatment process, and the production cost is reduced; and the specification range is wide. The method adopts the steps of electric furnace smelting, continuous casting and electroslag remelting smelting, the contents of P and S in the obtained tempered high-strength steel plate are low, and the steel is pure; and moreover, a large-slab electroslag remelting technology is adopted, the round ingot hammer cogging process during electroslag remelting is reduced, the production period is shortened, and the cost is obviously reduced.