The invention relates to a marine diesel engine sliding main bearing thermoelectricity signal calibration device. The diesel engine sliding main bearing thermoelectricity signal calibration device comprises an industrial computer, a programmable logic controller, a servo driver, a data acquisition card, a motor, a front supporting bearing, a rear supporting bearing, an experiment bearing, a rotate speed sensor, a thermoelectricity sensor, a torque sensor, a tile back temperature sensor, a lubricating oil temperature sensor, a lubricating oil pressure sensor, a hydraulic cylinder, a hydraulic oil tank, a hydraulic pump, a lubricating oil tank, a lubricating oil pump, a lubricating oil heater, a hydraulic sensor, and a displacement signal sensor. According to the technical scheme, a flexible feedback control strategy is adopted, the steady transition of rising and falling rotation speed and regulation of loading is guaranteed, a stable variable working condition is provided for testing the bearings, and thus dynamic calibration of thermoelectricity signals is achieved.