Three-dimensional Pt-Pb nano floricome type enzyme-free glucose sensor electrode as well as preparation and application thereof

A glucose sensor and nanoflower technology, applied in the direction of electrochemical variables of materials, can solve the problems of not easy to generate response current, slow overall kinetics, low sensitivity, etc., and achieve strong anti-interference ability, wide linear range, and good application prospects. Effect
CN101975807AActive Publication Date: 2011-02-16苏州盛泽科技创业园发展有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
苏州盛泽科技创业园发展有限公司
Publication Date
2011-02-16

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Abstract

The invention relates to a three-dimensional Pt-Pb nano floricome type enzyme-free glucose sensor electrode as well as preparation and application thereof. The electrode consists of a three-dimensional Pt-Pb nano floricome array on a stainless steel acupuncture needle substrate, wherein three-dimensional Pt-Pb nano floricomes exist on the surface of the electrode in a good crystallization form, and the diameter of the single nano floricome is 50-80nm. The preparation method comprises the following steps of: polishing a stainless steel acupuncture needle on deerskin; after the stainless steel acupuncture needle is repeatedly washed through secondary distilled water and processed through ultrasound, putting the stainless steel acupuncture needle in a PBS (Phosphate Buffer Solution) of whichthe pH is 7.0 to scan and activate for 10 circles through cyclic voltammetry; putting the stainless steel acupuncture needle into a hydrochloric acid electrolyte of 0.5mol / L, which consists of chloroplatinic acid and lead acetate by a ratio of 1:1; and preparing an electrode sample through an ultrasonic oscillation electro-deposition method. The three-dimensional Pt-Pb nano floricome type enzyme-free glucose sensor electrode has good electro-catalysis activity, wide linear response range and high sensitivity and selectivity.
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Description

technical field

[0001] The invention relates to a three-dimensional Pt-Pb nano-flower needle type enzyme-free glucose sensor electrode and its preparation and application. Background technique

[0002] In recent decades, research on electrochemical biosensors with immobilized glucose oxidase has achieved certain results, and has made great contributions to the invasive and noninvasive detection of blood glucose in diabetic patients. However, for the diagnosis and treatment of diabetes, the most important thing is the reproducible, accurate, fast, selective and cheap blood glucose monitoring in biological fluids. Although the enzyme-based sensor has good selectivity and sensitivity in the monitoring process, the enzyme is easily inactivated and denatured during the immobilization process, so the biggest problem with the enzyme-based sensor is poor stability; the second is the amount of immobilized enzyme It cannot be accurately controlled, so that the repeatability of the pr...

Claims

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