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Dissolvable nano web porous film and method of preparing the same

A mesh-like porous and porous film technology, which is applied in the manufacture of rayon, medical preparations of non-active ingredients, sheet-like delivery, etc., can solve the problem that the film does not have enough anti-adhesive properties, and achieve excellent solubility and rapid display of treatment Effect, the effect of preventing bad smell

Inactive Publication Date: 2011-04-13
GENIC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Treated starch is basically used alone, so the film does not have sufficient anti-sticking properties

Method used

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  • Dissolvable nano web porous film and method of preparing the same
  • Dissolvable nano web porous film and method of preparing the same
  • Dissolvable nano web porous film and method of preparing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0096] (1) Preparation of a polymer solution for forming a nano-network porous membrane

[0097] Add 1.5% by weight of microcrystalline cellulose to 70% by weight of distilled water, and disperse fully and uniformly at room temperature for about 10 minutes. 0.6% by weight of sucrose fatty acid ester was added to this solution and completely dissolved. Then, add 0.3% by weight of sorbitol, 0.8% by weight of propylene glycol and 0.4% by weight of glycerol to the resulting solution, heat to 70°C, slowly add 23% by weight of pullulan in the heated solution, and stir until completely dissolved In solution. The formed solution was heated to 80° C., 0.13 wt % carrageenan, 0.13 wt % carob gum (LBG) and 0.13 wt % xanthan gum were added to the heated solution to completely disperse and dissolve. After the resulting solution was cooled to 40° C., 0.46% by weight of aspartame, 0.04% by weight of acesulfame K, 0.3% by weight of malic acid, 2% by weight of menthol and 0.21% by weight of c...

Embodiment 2

[0112] Add 1.5% by weight of microcrystalline cellulose to 70% by weight of distilled water, and disperse fully and uniformly at room temperature for about 10 minutes. 0.6% by weight of sucrose fatty acid ester was added to this solution and completely dissolved. Then, add 0.3% by weight of sorbitol, 0.8% by weight of propylene glycol and 0.4% by weight of glycerol to the resulting solution, heat to 70°C, slowly add 23% by weight of pullulan in the heated solution, and stir until completely dissolved in solution. The formed solution was heated to 80° C., 0.1 wt % carrageenan, 0.1 wt % carob gum (LBG) and 0.1 wt % xanthan gum were added to the heated solution to completely disperse and dissolve. After the resulting solution was cooled to 40° C., 0.5% by weight of aspartame, 0.1% by weight of acesulfame K, 0.3% by weight of malic acid, 2% by weight of menthol and 0.2% by weight of citric acid were added to the solution, and then Stir until they are uniformly dispersed and comple...

Embodiment 3

[0116] Add 0.6% by weight of sucrose fatty acid ester to 71.41% by weight of distilled water, and disperse fully and uniformly at room temperature. Then, 0.3% by weight of sorbitol, 0.9% by weight of propylene glycol, and 0.4% by weight of glycerin were added to the solution, and heated to 70°C. 23% by weight of hydroxypropylmethylcellulose (HPMC) was slowly added to the heated solution, and stirred until completely dissolved in the solution. The formed solution was heated to 80° C., 0.1 wt % carrageenan, 0.1 wt % carob gum (LBG) and 0.1 wt % xanthan gum were added to the heated solution to completely disperse and dissolve. After the resulting solution was cooled to 40° C., 0.45% by weight of aspartame, 0.04% by weight of acesulfame K, 0.3% by weight of malic acid, 2% by weight of menthol and 0.3% by weight of citric acid were added to the solution, and then Stir until they are uniformly dispersed and completely dissolved, thus preparing a polymer solution. The porous membra...

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Abstract

A dissolvable nano web porous film has a network structure and a large specific surface area. The network structure is formed by stacking nano fibers that have a thickness of 10-50,000 nm. The nano fibers are formed of a composition comprising a nano fiber forming polymer, a gelling agent, a plasticizer, an optional active component and an optional additive. A method of preparing a dissolvable nano web film comprises producing a polymer melt or solution formed of a composition that comprises a nano fiber forming polymer, a gelling agent, a plasticizer, an optional active component and additives, spinning the melt or solution to form a nano web porous film having nano webs stacked in a network structure, drying the nano web porous film, and stabilizing the nano web porous film. The porous film has a 5-5000 times higher specific surface area and a 2-20 times faster dissolving time than a conventional film. The dissolvable nano web porous film has excellent dissolvability and solubility.

Description

technical field [0001] The present invention relates to a dissolvable nano-network porous membrane that can be used in biology or physiology, and a manufacturing method of the porous membrane. More specifically, the present invention relates to a nano-network porous membrane with a nano-network structure and a large specific surface area and a method for manufacturing the same. Background technique [0002] In general, conventional edible non-porous films can be produced by combining polymers such as starch, pullulan, etc. Agents, surface active agents, stabilizers, emulsifiers, thickeners, binders, colorants, pigments, sweeteners, fragrances, antimicrobial agents, etc. are dissolved in a solvent such as water to provide a mixture; The mixture is formed into a film, which is then dried; the obtained film is cut into films of appropriate size; and they are placed in containers. [0003] Conventional edible non-porous films are required to have excellent solubility in the mo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/30C08J5/18G02B1/11A61C19/06
CPCA61K9/70D01F1/10A61K47/30A61K9/0056Y02A50/30A61K9/20
Inventor 刘眩旿孙泰垣
Owner GENIC
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