Qingpeng nasal preparation for stopping pain and diminishing swelling and preparation method thereof

Abstract

The invention discloses a Qingpeng nasal preparation for stopping pain and diminishing swelling, which is prepared by taking the prescription of traditional Tibetan medicine of Qingpeng ointment as a basic prescription and changing a formulation, and a preparation method thereof. The Qingpeng nasal preparation is prepared by a method that particle medicinal materials are extracted and partial medicinal materials are subjected to ultra-fine crushing, effectively maintains active ingredients of the medicinal materials, greatly improves the content of crude medicines, and improves bioavailability to make treatment effect better. Auxiliary materials selected have good mouldability, so that the product has good permeability, and is better to absorb and quick in response. The Qingpeng nasal preparation has the advantages of convenience of administration, long duration, low allergy rate, convenience of use, portability, no pollution to clothes and the like. A nasal mucosal medicine delivery system is adopted, is quick in absorption and response, and does not have any stimulation or odor. Pharmacodynamic experiments prove that the Qingpeng powder or granules have obvious effects of stopping pain and diminishing swelling.

Description

Field of Invention [0001] The invention relates to a Qingpeng nasal preparation and a preparation method thereof, in particular to a Qingpeng nasal preparation used for relieving pain and swelling and a preparation method thereof. technical background [0002] Qingpeng ointment is a classic Tibetan medicine prescription composed by Tibetan folk doctors according to the records of "Tibetan Medicine and Medical Supplements and Interpretation Difficulties" and "Four Medical Classics" and combined with practical experience. The first volume of medicine, 322 pages. Qingpeng ointment is prescribed as: [0003] 100g sickle thorn bean, 50g rhubarb, 75g iron club hammer, 100g myrobalan, 100g myrobalan, 100g amla japonica, 35g benzoin, 150g wide tendon vine, 25g musk. [0004] Preparation method: The above nine flavors are ground into fine powder except musk, which is separately ground into fine powder, sieved, added musk fine powder, mixed well, and mixed with 8-year-old child urin...

AI Technical Summary

Problems solved by technology

[0015] According to the records of "Four Medical Codes" and "Jingzhu Materia Medica", combined with long-term practical experience, Tibetan folk doctors use Oxytropis falciparum, sub-rhubarb, iron bar hammer, myrobalan, myrobalan, emblica, benzoin, and gluten The Tibetan medicine Qingpeng ointment produced from rattan and musk is trusted by the majority of patients for its remarkable therapeutic effect. However, the traditional preparation process of Tibetan medicine Qingpeng ointment is to mix all the original medicinal materials with fine powder to make ointment. The process is complicated. The batch production cycle is long and the production process is unstable; the sources of raw materials and excipients are unstable, which is not conducive to industrial production; some drugs have poor penetration ability and low bioavailability, so the curative effect cannot be fully guaranteed, and the curative effect of the drug is not suitable; in addition, the product is not suitable for storage and carrying. Inconvenient; Due to various reasons, it greatly affects the efficacy and promotion of the product

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