Medical powder inhalation and application thereof

A technology of powder mist and powder, applied in the field of medical supplies, to achieve the effect of low cost, convenient use and stable quality

Inactive Publication Date: 2011-05-18
云南白药集团无锡药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the powder aerosol made of chitosan and its derivatives as main components is still a blank of research
Although the patent application number 200610045418.X discloses the preparation and application of powder mist and granules with chitosan derivatives as main components, the formula disclosed in this patent is only the powder of chitosan derivatives Mixed with other powders, granules made by packaging and sterilization are not real powder sprays

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Put 1.5g of carboxymethyl chitosan and 8.0g of isopropanol in a container, stir well at room temperature, wait for them to mix and disperse evenly, pour them into an aluminum can, and seal it. On the aerosol pressure filling canning line, 80.0g of propane-containing liquefied butane gas (the volume ratio of propane to butane is 1:1) and 10.5g of carbon dioxide gas are canned into aluminum cans to obtain finished products .

Embodiment 2

[0047] Put 1.0g hydroxypropyl chitin, 3.0g methylal, 0.5g calcium alginate, 0.1g nano-silver, and 0.01g ibuprofen in a container, stir fully at room temperature, wait for them to mix and disperse evenly, pour Put into aluminum cans and seal. To the aerosol pressure filling canning line, 88.0g of tetrafluoroethane and 7.39g of carbon dioxide gas are canned into aluminum cans to obtain finished products.

Embodiment 3

[0049] Put 15.0g of chitosan acetate, 15.0g of acetone, 0.5g of Yunnan Baiyao, and 0.1g of sodium silver zirconium phosphate in a container, stir well at room temperature, wait for the mixture to disperse evenly, pour it into an aluminum can, and seal it . On the aerosol pressure filling canning line, 60.0g of propane-containing liquefied butane gas (the volume ratio of propane to butane is 1:5) and 9.4g of carbon dioxide gas are canned into aluminum cans to obtain the finished product .

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PUM

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Abstract

The invention relates to medical powder inhalation and application thereof. The medical dust powder inhalation mainly comprises a chitosan derivative, a latent solvent, a propellent and an inert substance as well as also possibly comprises optional functional substances of haemostatic, an antibacterial agent, analgesic and surfactant. The chitosan derivative powder, the latent solvent, the haemostatic powder, the antibacterial agent powder, the analgesic powder and the surfactant are placed into a reaction vessel, fully stirred at room temperature, uniformly mixed and dispersed to obtain a suspension; and the suspension, the propellent and the inert substance are simultaneously packed into subpackaged cans on an aerosol pressure excited filling and packing line to obtain the powder product. The invention also has obvious effects of stopping bleeding on a wound, relieving pain and speeding up repairing and healing of the wound besides the advantages of the traditional medical product, and has the advantages of stable quality, low cost, use convenience, no pollution to the atmosphere and high safety.

Description

technical field [0001] The invention relates to the field of medical supplies made of biological materials, in particular to a medical powder and its application. Background technique [0002] Wound repair is one of the basic problems faced by the fields of pharmacy, medicine and materials, but until the last 30 years, with the rapid development of materials technology, people have gradually paid more attention to it and become the focus of research. Traditional cotton gauze dressings have been gradually eliminated due to the pain of dressing change caused by the adhesion of wound tissue during use, secondary trauma, and poor therapeutic effect on refractory wounds such as ulcers. Instead, there are some high-tech wet dressings suitable for "wet therapy", such as hydrocolloid, hydrogel, film, foam and other dressings. Some materials with good usability and biocompatibility are used in these dressings, including hyaluronic acid. acid, carboxymethyl cellulose, sodium alginate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/00A61K31/722A61K9/12A61P17/02A61P7/04A61P31/04
Inventor 周应山江海
Owner 云南白药集团无锡药业有限公司
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