Self-heating type Chinese medicinal emplastrum for treating proliferation of mammary gland

A kind of breast hyperplasia, self-heating technology, applied in the direction of heating device for treatment, cooling device for treatment, drug combination, etc.

Active Publication Date: 2012-04-18
烟台美美丁健康产业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drug is an oral formulation,

Method used

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  • Self-heating type Chinese medicinal emplastrum for treating proliferation of mammary gland

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Self-heating traditional Chinese medicine plaster group:

[0057] 1. Preparation of plaster:

[0058] Prescription of raw materials: borneol 8g, orange core 120g, trigonum 56g, zedoary zedoary 56g, rhubarb 80g, blancia 80g.

[0059] Matrix formula: 31g gelatin, 12g sodium carboxymethylcellulose, 8g polyvinyl alcohol, 88g pressure-sensitive adhesive, 24g carbomer, 250g glycerol, 250g propylene glycol, 5g kaolin, 5g zinc oxide, 9g citric acid, citric acid Sodium 33g, water 285g.

[0060] Preparation of water extract: Add water to decoct orange core, trigonum, curcuma, rhubarb and blanc blanc twice, add 6 times the amount of water for the first time, add 6 times the amount of water for the second time, each time for 1.5 hours, combine The second decoction is filtered, the filtrate is concentrated to a thick paste with a relative density of 1.28-1.32 (measured at 60°C), dried at 80°C, crushed into fine powder, and sieved to obtain the product.

[0061] Preparation of act...

Embodiment 2

[0069] 1. Preparation of plaster:

[0070] Prescription of raw materials: borneol 6g, orange core 97g, trigonum 44g, zedoary zedoary 58g, rhubarb 106g, blancia 89g.

[0071] Matrix formula: 37g gelatin, 14g sodium carboxymethylcellulose, 10g polyvinyl alcohol, 307g glycerol, 306g propylene glycol, 50g polyethylene glycol, 50g butanediol, 6g zinc oxide, 6g micronized silica gel, 29g sodium citrate , aluminum trichloride 8g, water 177g.

[0072] Preparation of water extract: same as Example 1.

[0073] Preparation of active ingredients: add borneol to the prepared water extract, mix well to obtain Chinese medicine extract powder.

[0074] Preparation of plaster: dissolve the prepared active ingredients in water, add propylene glycol, glycerin, polyethylene glycol and butylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, fully swell, Component 1 is obtained; sodium carboxymethyl cellulose is dissolved in 1 / 6 of the a...

Embodiment 3

[0081] 1. Preparation of plaster:

[0082] Prescription of raw materials: 11g borneol, 162g orange core, 20g trigonum, 34g curcuma, 77g rhubarb, 96g blanc.

[0083] Matrix formula: 40g gelatin, 17g sodium carboxymethylcellulose, 17g methylcellulose, 11g sodium polyacrylate, 11g polyvinyl alcohol, 11g polyvinylpyrrolidone, 125g pressure-sensitive adhesive, 33g carbomer, 156g glycerol, Propylene glycol 156g, micropowder silica gel 8g, citric acid 15g, sodium citrate 27g, water 373g.

[0084] Preparation of water extract: same as Example 1.

[0085] Preparation of active ingredients: add borneol to the prepared water extract, mix well to obtain Chinese medicine extract powder.

[0086] Preparation of plaster: dissolve the prepared active ingredients in water, add glycerol and propylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, and fully swell to obtain component 1; gelatin, carboxylate Sodium methyl cellulose, met...

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Abstract

The invention relates to a Chinese medicinal compound preparation, in particular to a self-heating type Chinese medicinal emplastrum for treating the proliferation of mammary gland. The self-heating type Chinese medicinal emplastrum consists of a sealing bag, and plaster and a self-heating bag which are wrapped in the sealing bag and are bonded together from top to bottom; the self-heating bag consists of a breathable bag and chemical heating materials which are wrapped in the breathable bag and are used for iron oxidation and reduction reaction; and the plaster consists of a back lining layer, a drug storage layer and an anti-adhesive layer. The self-heating type Chinese medicinal emplastrum is characterized in that the drug storage layer consists of pharmaceutically-acceptable matrix and effective components of bulk drugs with the weight being 40% of that of the matrix, wherein the effective components include 1.5%-3% of borneol and aqueous extracts of the following materials according to the weight percentage of the bulk drug: 20%-50% of tangerine seed, 5%-20% of rhizoma sparganii, 5%-20% of curcuma zedoary, 10%-30% of rheum officinale and 10%-30% of cowherb seed. The self-heating type Chinese medicinal emplastrum has the advantages of fast effect, good transdermal absorption and exact curative effect.

Description

field of invention [0001] The invention relates to medical preparations, in particular to an external patch for improving mammary gland hyperplasia. technical background [0002] Mammary gland hyperplasia refers to hyperplasia of mammary gland epithelium and fibrous tissue, structural degeneration of breast tissue ducts and lobules, and progressive growth of connective tissue. The main cause of the disease is endocrine hormone imbalance. According to the survey, about 70% to 85% of women have different degrees of breast hyperplasia. According to the latest survey, mammary gland hyperplasia has become the most common breast problem in women. Seen in women aged 20 to 45, or 30% to 45% of women of childbearing age. Modern medicine thinks: the external environment of marriage and childbirth, diet, people's survival and genetic factors are the main causes of mammary gland morbidity. Breast hyperplasia is the most common breast disease in women and should be prevented in advance...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/70A61F7/03A61P15/14
Inventor 方永奇方惠新刘林薛中锋方若鸣
Owner 烟台美美丁健康产业有限公司
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