2-methyl-4-chlorophenoxy acetic acid and 2-methyl-4-chlorophenoxy acetic acid salt water-dispersible granule or tablet and preparation method thereof
A technology of dimethyl tetrachloride brine and dimethyl tetrachloride, which is applied in the fields of botanical equipment and methods, herbicides, algicides, biocides, etc., and can solve the problems of easy drift, inaccurate measurement, and small soluble powder particles problems, to achieve the effect of simple preparation process, accurate measurement, and not easy to be harmed by phytotoxicity
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Embodiment 1
[0033] The preparation of embodiment 1 5% dimethyl tetrachloride water dispersible granules
[0034] The selection and proportioning of the original medicine and auxiliary agents are: 95% dimethyltetrachloride original medicine 5.3% (5% discount), the dispersant is 2.0% sodium methylene dimethyl naphthalene sulfonate, 4.0% calcium lignosulfonate %, wetting agent sodium lauryl sulfate 2.0%, disintegrating agent is ammonium sulfate 15.0%, binder is dextrin 5.0%, filler is attapulgite to make up 100%
[0035] According to the above proportions, the dosage of each component is calculated, weighed, and mixed evenly; the formula is granulated by ultrafine / jet milling, dried, granulated, and selected. Product testing is carried out according to the quality control indicators of water-dispersible granules, including the content of active ingredients, wetting time, disintegration rate, suspension rate, foaming property, sieve analysis, shedding rate, pH range and thermal storage stabil...
Embodiment 2
[0043] The preparation of embodiment 2 5% dimethyl tetrachloride water dispersible tablets
[0044] The selection and proportioning of the original drug and auxiliary agent are: 5.3% (5% discount) of the original drug of 95% dimethyltetrachloride, the dispersant is 3.0% of naphthalenesulfonate formaldehyde condensate, 3.0% of calcium lignosulfonate, moistening agent The wet agent is sodium lauryl sulfate 2.0%, the disintegrant is ammonium sulfate 17.0%, the binder is polyvinyl alcohol 5.0%, and the filler is talcum powder to make up 100%.
[0045] According to the above proportions, the dosage of each component is calculated, weighed, and mixed evenly; the formula is granulated by ultrafine / jet milling, dried, pressed into tablets, and selected. Product testing is carried out according to the quality control indicators of water-dispersible tablets, including the content of active ingredients, disintegration time limit, suspension rate, foaming property, sieve analysis, powder ...
Embodiment 3
[0054] Embodiment 3 Preparation of 5% Sodium Dimethyltetrachloride Water Dispersible Granules
[0055] The selection and ratio of original drug and auxiliary agent are: 95% sodium dimethyltetrachloride original drug 5.3% (5% discount), dispersant is 2.0% sodium methylene bismethyl naphthalene sulfonate, calcium lignosulfonate 4.0%, wetting agent sodium lauryl sulfate 2.0%, disintegrating agent is microcrystalline cellulose sodium 15.0%, binder is dextrin 5.0%, filler is attapulgite to make up 100%
[0056] According to the above proportions, the dosage of each component is calculated, weighed, and mixed evenly; the formula is granulated by ultrafine / jet milling, dried, granulated, and selected. Product testing is carried out according to the quality control indicators of water-dispersible granules, including the content of active ingredients, wetting time, disintegration rate, foaming property, sieve analysis, shedding rate, pH range and thermal storage stability, etc. The sp...
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