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Medicinal composition for treating functional constipation

A functional constipation and composition technology, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as unfavorable long-term application, increased colon tension, and fecal incontinence, so as to enhance intestinal propulsion, improve defecation volume, The effect of drug safety

Inactive Publication Date: 2013-04-24
如东新宇科技创业园有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Stimulant laxatives have strong and rapid effects, and are mostly used for patients with fecal impaction and rapid defecation. They are not suitable for long-term use, because they stimulate the intestinal mucosa and intestinal wall nerve plexus, improve the permeability of the mucosa, and affect intestinal water, electrolytes and vitamins. Absorption and even disorder can also cause weakness of the large intestine muscle, resulting in drug dependence and fecal incontinence; volumetric laxatives can increase the volume of stool, but cannot effectively increase the tension of the colon, and the use of intestinal sluggishness is limited; lubricating laxatives have poor taste , the effect is weak, and long-term use can cause adverse reactions such as fat-soluble vitamin absorption disorders and perianal oily leakage; osmotic laxatives such as lactulose are not absorbed in the small intestine, they are decomposed by colonic bacteria and release organic acids. Endogenous effect, there are disadvantages such as abdominal distension or abdominal pain, poor curative effect after long-term application, and easy to cause changes in intestinal flora; intestinal motility drugs often need to be used in combination with other drugs, and the side effects are also relatively large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The preparation of embodiment 1 Chinese medicine oral liquid

[0038] Herbal medicine prescription: Magnolia officinalis 8 parts, betel nut 10 parts, licorice 8 parts, scutellaria baicalensis 12 parts, angelica 15 parts, Cistanche 10 parts, Rehmannia glutinosa 20 parts, fried Atractylodes macrocephala 20 parts.

[0039] Preparation:

[0040] The first step, prepare clear cream powder:

[0041] 1) Material preparation: Weigh the above-mentioned Chinese medicinal materials cleaned according to the prescription amount, and set aside;

[0042] 2) Decoction: add water for decoction, add water to each pot for the first decoction, which is 8 times the total amount of medicinal materials, heat and boil for 3 hours, and the extract is filtered through a 200-mesh filter and enters the sedimentation tank; for the second decoction, add 4 times the amount of medicinal materials The water is heated and extracted, kept boiling for 3 hours, and the extract is filtered through a 200-...

Embodiment 2

[0049] The preparation of embodiment 2 Chinese medicine oral liquid

[0050] Herbal medicine prescription: Magnolia officinalis 6 parts, betel nut 12 parts, licorice 8 parts, scutellaria baicalensis 15 parts, angelica 12 parts, Cistanche 8 parts, Rehmannia glutinosa 25 parts, fried Atractylodes macrocephala 18 parts.

[0051] Preparation:

[0052] The first step, prepare clear cream powder:

[0053] 1) Material preparation: Weigh the above-mentioned Chinese medicinal materials cleaned according to the prescription amount, and set aside;

[0054] 2) Decoction: add water for decoction, add water to each pot for the first decoction, which is 8 times the total amount of medicinal materials, heat and boil for 3 hours, and the extract is filtered through a 200-mesh filter and enters the sedimentation tank; for the second decoction, add 4 times the amount of medicinal materials The water is heated and extracted, kept boiling for 3 hours, and the extract is filtered through a 200-...

Embodiment 3

[0061] The preparation of embodiment 3 Chinese medicine oral liquid

[0062] Herbal medicine prescription: Magnolia officinalis 10 parts, betel nut 10 parts, licorice 10 parts, scutellaria baicalensis 10 parts, angelica 15 parts, cistanche 12 parts, Rehmannia glutinosa 25 parts, fried Atractylodes macrocephala 25 parts.

[0063] Preparation:

[0064] The first step, prepare clear cream powder:

[0065] 1) Material preparation: Weigh the above-mentioned Chinese medicinal materials cleaned according to the prescription amount, and set aside;

[0066] 2) Decoction: add water for decoction, add water to each pot for the first decoction, which is 8 times the total amount of medicinal materials, heat and boil for 3 hours, and the extract is filtered through a 200-mesh filter and enters the sedimentation tank; for the second decoction, add 4 times the amount of medicinal materials The water is heated and extracted, kept boiling for 3 hours, and the extract is filtered through a 2...

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Abstract

The invention discloses a medicinal composition for treating functional constipation and relates to the technical field of Chinese medicines. The medicinal composition is prepared from the following Chinese herbal medicines in part by weight: 6 to 10 parts of officinal magnolia mark, 8 to 12 parts of areca seed, 6 to 10 parts of liquoric root, 10 to 15 parts of baical skullcap root, 12 to 16 parts of Chinese angelica, 8 to 12 parts of desertliving cistanche, 18 to 25 parts of prepared rehmannia root and 18 to 25 parts of prepared largehead atractylodes rhizome. The medicinal composition for treating the functional constipation has the advantages of good curative effect and high safety.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating functional constipation. Background technique [0002] Chronic constipation is a common symptom with complex etiology, which brings a lot of distress to patients and seriously affects the quality of life of patients. With the development of society, the increase of survival pressure, fierce competition, and the change of living habits such as diet structure, the incidence of constipation is on the rise. [0003] In terms of diagnosis, pathophysiology and treatment of functional gastrointestinal diseases, including constipation, the Rome I criteria were launched in 1994, and the Rome II criteria were launched in 2000. The international concept of constipation takes the Rome II standard as the general standard. Constipation refers to dry stool, difficulty in defecation or feeling of incomplete defecation and decreased...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61P1/10
Inventor 程波
Owner 如东新宇科技创业园有限公司