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Effervescent tablet for false teeth as well as preparation method and application of effervescent tablet

A technology for effervescent tablets and dentures, which is used in dentistry, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of time-consuming and laborious, damage to the surface finish of dentures, and deformation of dentures, and achieves the effect of convenient use and high cleaning efficiency.

Active Publication Date: 2013-06-12
NANJING SHENGDE INST OF BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The traditional method of cleaning dentures is to use common detergents such as toothpaste, tooth powder, soapy water, detergent, and even hydrogen peroxide. Dentures are deformed, and brushing with a hard brush will destroy the chemical structure of the denture material and affect the service life of the denture

Method used

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  • Effervescent tablet for false teeth as well as preparation method and application of effervescent tablet
  • Effervescent tablet for false teeth as well as preparation method and application of effervescent tablet
  • Effervescent tablet for false teeth as well as preparation method and application of effervescent tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The preparation of embodiment 1 effervescent tablet-formula 1

[0036] formula:

[0037] No. Raw material Mass (g)

[0038] 1 citric acid 20.0

[0039] 2 NOBS 2.55

[0040] 3 Sodium carboxymethyl starch 2.2

[0041] 4 Talc powder 0.5

[0042] 5 Potassium bicarbonate 34.0

[0043] 6 Sodium percarbonate 30.0

[0044] 7 Sodium perborate 5.0

[0045] 8 Potassium persulfate 5.0

[0046] 9 Protease 0.5

[0047] 10 Menthol 0.25

[0048] Steps:

[0049] 1. Mix citric acid, NOBS, sodium carboxymethyl starch, talcum powder, etc., and grind them;

[0050] 2. Then add potassium bicarbonate, menthol and protease, etc., mix and pulverize;

[0051] 3. Then add sodium percarbonate, sodium perborate and potassium persulfate, and stir evenly;

[0052] 4. After the powder is mixed, it is compressed into tablets by a tablet machine to obtain effervescent tablets 1.

Embodiment 2

[0053] The preparation of embodiment 2 effervescent tablet-formula 2

[0054] formula:

[0055] No. Raw material Mass (g)

[0056] 1 Tartaric acid 10.0

[0057] 2 Citric acid 9.5

[0058] 3 NOBS 0.75

[0059] 4 TAED 2.0

[0060] 5 Polyvinylpyrrolidone 2.0

[0061] 6 Talc powder 0.5

[0062] 7 Potassium bicarbonate 34.0

[0063] 8 Sodium percarbonate 30.0

[0064] 9 Sodium perborate 10.0

[0065] 10 Potassium persulfate 0.5

[0066] 11 Proteolytic enzyme 0.5

[0067] 12 Menthol 0.25

[0068] Steps:

[0069] 1. Mix tartaric acid, citric acid, NOBS, TAED, polyvinylpyrrolidone, talcum powder, etc., and then pulverize;

[0070] 2. Then add potassium bicarbonate, menthol and protease, etc., mix and pulverize;

[0071] 3. Then add sodium percarbonate, sodium perborate and potassium persulfate, and stir evenly;

[0072] 4. After the powder is mixed, it is compressed into tablets by a tablet machine to obtain effervescent tablets 2.

Embodiment 3

[0073] Preparation of Example 3 Effervescent Tablets-Formula 3

[0074] formula:

[0075] No. Raw material Mass (g)

[0076] 1 malic acid 20.75

[0077] 2 NOBS 1.0

[0078] 3 COBS 1.0

[0079] 4 Polyvinylpyrrolidone 2.0

[0080] 5 Talc powder 0.5

[0081] 6 Potassium bicarbonate 34.0

[0082] 7 Sodium percarbonate 30.0

[0083] 8 Sodium persulfate 10.0

[0084] 9 Protease 0.5

[0085] 10 Menthol 0.25

[0086] Operation steps embodiment 1, get effervescent tablet 3.

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Abstract

The invention belongs to the field of medicinal preparations and relates to an effervescent tablet for false teeth as well as a preparation method and application of the effervescent tablet. The effervescent tablet contains an oxygen releasing agent, carbonate or bicarbonate, an acidic raw material, an accelerator and a tablet accessory, wherein the oxygen releasing agent is selected from peroxide; the acidic raw material is selected from one of citric acid, malic acid, tartaric acid and fumaric acid or a mixture of several kinds of the citric acid, the malic acid, the tartaric acid and the fumaric acid; the tablet accessory comprises a binding agent and a lubricating agent; and the accelerator is acyl oxy benzene sulphonate. The effervescent tablet obtained by the preparation method disclosed by the invention is a cleaning agent of the false teeth and has extremely-low activity superior to that of a conventional effervescent tablet, i.e. the effervescent tablet releases active oxygenat the very low temperature; and the effervescent tablet is suitable for various environments in daily life, is not influenced by weather and seasons and is very convenient to use; and the effervescent tablet can be used for quickly and effectively removing attachments and killing normal bacteria in an oral cavity, so that the smooth of the surfaces of the false teeth can be recovered.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and relates to a denture effervescent tablet and a preparation method and application thereof. Background technique [0002] The oral cavity is very prone to produce a large number of bacteria and microorganisms. There are more than 300 kinds of bacteria that have been identified. Some bacteria will continue to adhere to the surface of the dentures and form a sticky, colorless film called dental plaque. . Dental plaque is the main pathogenic factor of dental caries and periodontal disease. There are hundreds of millions of bacteria in each cubic millimeter of dental plaque. They will produce many harmful substances, damage the tooth itself and cause inflammation and inflammation of the tissues around the tooth. destroy. Periodontal disease, as the name suggests, is a disease of the tissues surrounding the teeth. The long-term accumulation of dental plaque forms dental calculus, which...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/46A61K8/365A61K8/362A61K8/22A61K8/19A61K8/66A61K8/02A61Q11/02
Inventor 苏桂珍史鲁秋李华山
Owner NANJING SHENGDE INST OF BIOTECHNOLOGY CO LTD