Amorphous hydrocolloid dressing

Abstract

The invention discloses amorphous hydrocolloid dressing formed by high-energy ray irradiation proper crosslinking. The amorphous hydrocolloid dressing disclosed by the invention has good deformability, film forming property, moisture retention, biocompatibility and wound healing facilitation, and can protect various surgical incisions, cover various acute and chronic wounds and wound surfaces, prevent infection, accelerate healing and relive cicatrization. The amorphous hydrocolloid dressing is suitable for the filling covering protection on various wounds with tissue defects and for the protection and treatment of the surgical incisions and burns and scales including the wound surfaces formed by chemical burns as well as various acute and chronic wounds and wound surfaces. Moreover, through radiation sterilization, the amorphous hydrocolloid dressing can be stored for a long time. The formula of the amorphous hydrocolloid dressing disclosed by the invention comprises the following components in percentage by weight: 2-8% of sodium carboxymethylcellulose, 1-6% of chitosan and the balance of water. The amorphous hydrocolloid dressing also can comprise 0.1-0.3% of silver nitrate or silver chloride, 3-8% of polyvinyl alcohol, 15-25% of propylene glycol and the like all by weight. The amorphous hydrocolloid dressing is subjected to high-energy ray irradiation proper crosslinking and sterilization, thus the irradiation dose is 5-15KGy.

Description

technical field

[0001] The invention relates to a filling dressing suitable for the protection and treatment of various wounds with tissue defects, surgical incisions, wounds formed by burns and scalds including chemical burns, various acute and chronic wounds, and the protection and treatment of wounds. Amorphous hydrocolloid dressings. Background technique

[0002] At present, the composite medical dressings used for the protection and treatment of various surgical incisions, wounds and wounds mainly include the following types:

[0003] (1) Coating medical pressure-sensitive adhesive on polyvinyl chloride, polyethylene, polypropylene, non-woven polyurethane and other backing materials, and directly pasting the prepared film on the wound surface as a medical dressing.

[0004] (2) three-layer composite medical dressing, usually with a breathable continuous film as a protective backing layer; non-woven fabrics, foam materials or fiber fabrics, etc. become.

[0005] (3) H...

Examples

Embodiment 1

[0016] Weigh 200 grams of sodium carboxymethyl cellulose and 150 grams of chitosan, add 4650 grams of water, fully stir and dissolve with a constant temperature mixer, let it stand for 30 minutes, take out the solution and add it to the filling machine, and put it into 100 ml plastic tubes Seal it in the middle, put it into the cobalt source irradiation room to irradiate 10KGy, and get it after taking it out.

Embodiment 2

[0018] Weigh 150 grams of sodium carboxymethyl cellulose, 200 grams of chitosan, 0.5 grams of silver nitrate or silver chloride, add 4649.5 grams of water, fully stir and dissolve with a constant temperature mixer, let stand for 30 minutes, take out the solution and add it to the filling machine , put them into 100ml plastic tubes and seal them respectively, put them into the cobalt source irradiation room and irradiate 6KGy, and then take them out to obtain.

Embodiment 3

[0020] Weigh 125 grams of sodium carboxymethyl cellulose, 175 grams of chitosan, 150 grams of polyvinyl alcohol, and 1,000 grams of propylene glycol, add 3,550 grams of water, fully stir and dissolve with a constant temperature mixer, let it stand for 45 minutes, take out the solution and add it to the filling In the machine, put them into 100 ml plastic tubes and seal them respectively, put them into the cobalt source irradiation room and irradiate 15KGy, and get the product after taking them out.

technical field

[0001] The invention relates to a filling dressing suitable for the protection and treatment of various wounds with tissue defects, surgical incisions, wounds formed by burns and scalds including chemical burns, various acute and chronic wounds, and the protection and treatment of wounds. Amorphous hydrocolloid dressings. Background technique

[0002] At present, the composite medical dressings used for the protection and treatment of various surgical incisions, wounds and wounds mainly include the following types:

[0003] (1) Coating medical pressure-sensitive adhesive on polyvinyl chloride, polyethylene, polypropylene, non-woven polyurethane and other backing materials, and directly pasting the prepared film on the wound surface as a medical dressing.

[0004] (2) three-layer composite medical dressing, usually with a breathable continuous film as a protective backing layer; non-woven fabrics, foam materials or fiber fabrics, etc. become.

[0005] (3) H...

Examples

Embodiment 1

[0016] Weigh 200 grams of sodium carboxymethyl cellulose and 150 grams of chitosan, add 4650 grams of water, fully stir and dissolve with a constant temperature mixer, let it stand for 30 minutes, take out the solution and add it to the filling machine, and put it into 100 ml plastic tubes Seal it in the middle, put it into the cobalt source irradiation room to irradiate 10KGy, and get it after taking it out.

Embodiment 2

[0018] Weigh 150 grams of sodium carboxymethyl cellulose, 200 grams of chitosan, 0.5 grams of silver nitrate or silver chloride, add 4649.5 grams of water, fully stir and dissolve with a constant temperature mixer, let stand for 30 minutes, take out the solution and add it to the filling machine , put them into 100ml plastic tubes and seal them respectively, put them into the cobalt source irradiation room and irradiate 6KGy, and then take them out to obtain.

Embodiment 3

[0020] Weigh 125 grams of sodium carboxymethyl cellulose, 175 grams of chitosan, 150 grams of polyvinyl alcohol, and 1,000 grams of propylene glycol, add 3,550 grams of water, fully stir and dissolve with a constant temperature mixer, let it stand for 45 minutes, take out the solution and add it to the filling In the machine, put them into 100 ml plastic tubes and seal them respectively, put them into the cobalt source irradiation room and irradiate 15KGy, and get the product after taking them out.