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Traditional Chinese medicine for prevention and treatment of pullorum disease, preparation method thereof and feed

A technology of traditional Chinese medicine and feed additive, which is applied in the field of traditional Chinese veterinary medicine, can solve the problems of endangering human health, increased drug resistance of Salmonella chicken, and drug resistance of pathogenic bacteria, and achieves the effects of low price, no drug resistance, and small toxic and side effects

Active Publication Date: 2012-09-12
SHANDONG NEW HOPE LIUHE GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the commonly used method for preventing and treating pullorum disease is to rely on antibiotics and sulfonamides and other western medicines. Although certain curative effects have been obtained, the widespread and unreasonable use of antibiotics has caused the drug resistance of Salmonella chickens to increase year by year. It not only causes drug resistance of pathogenic bacteria, but also causes drug resistance of conditional pathogenic bacteria and symbiotic bacteria in the body, and drug resistance can be transmitted to the population through the food chain, which also endangers human health

Method used

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  • Traditional Chinese medicine for prevention and treatment of pullorum disease, preparation method thereof and feed

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preparation example Construction

[0056] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine composition decoction, which includes:

[0057] In the first step, the components are mixed in proportion and pulverized;

[0058] In the second step, add water 2 to 4 times the mass of the mixture to the pulverized mixture, decoct for 2 to 4 hours, filter, add water 1 to 2 times the mass of the mixture to the filter residue and decoct again After 1-2 hours, filter, mix the two filtrates, and concentrate under reduced pressure until the crude drug concentration is 1g / ml-3g / ml.

[0059] The present invention also provides the preparation method of above-mentioned traditional Chinese medicine composition powder, it comprises:

[0060] In the first step, the components are put into the mixer according to the proportion and stirred for 30-50 minutes, fully mixed and pulverized;

[0061] In the second step, add water 2 to 4 times the mass of the mixture to the pulve...

Embodiment 1

[0085] Embodiment 1 The toxicity test of Chinese medicine composition of the present invention

[0086] Mix 39g Coptidis, 19g Sophorae, 49g Pulsatilla, 42g Anemarrhena, 21g Prunella vulgaris, 30g Honeysuckle, 18g Scrophulariae, 32g Codonopsis Codonopsis, 26g Atractylodes macrocephala, 22g lotus seeds, 18g ebony, 16g pomegranate peel, 14g coix seed, and crush them; Add 1000g of water to the crushed mixture, decoct for 3 hours, filter, add 400g of water to the filter residue and decoct for 2 hours again, filter, mix the two filtrates, concentrate under reduced pressure to a decoction with a crude drug concentration of 3g / ml .

[0087] Take ICR mice with a body weight of 25-30 grams, and randomly divide them into groups according to body weight, 10 mice in each group, half male and half male, and administer the solution orally, and the dosage is 5.8ml / mouse. Continuous observation for 20 days after administration showed that all the mice survived, and no abnormalities were found...

Embodiment 2

[0089] The preparation of embodiment 2 Chinese medicine composition decoction

[0090] Mix 390g coptis, 190g flavescens, 490g pulsatilla, 420g Anemarrhena, 210g Prunella vulgaris, 300g honeysuckle, 180g crocodile, 320g Codonopsis, 260g Atractylodes macrocephala, 220g lotus seeds, 180g ebony plum, 160g pomegranate peel, 140g coix seed, and grind them; Add 1000g of water to the pulverized mixture, decoct for 3 hours, filter, add 400g of water to the filter residue and decoct for 2 hours, filter, mix the two filtrates, concentrate under reduced pressure to a decoction with a crude drug concentration of 1.5g / ml agent.

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Abstract

The invention provides traditional Chinese medicine for prevention and treatment of pullorum diseases, which comprises coptis chinensis, radix sophorae flavescentis, pulsatilla chinensis, rhizoma anemarrhenae, selfheal, honeysuckle, radix scrophulariae, codonopsis pilosula, rhizoma atractylodis macrocephalae, lotus seeds, dark plum, granatum and semen coicis. The traditional Chinese medicine has the advantages of high efficacy, fewer toxic and side effects, no residues, no resistance to drugs, no environmental pollution, capability of improving the body resistance, short treatment course, rapid effects and wide scope of promotion and application in prevention and treatment of chicken suffering from pullorum diseases.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese veterinary medicine, in particular to a traditional Chinese medicine for preventing and treating pullorum. Background technique [0002] Pullorum has always been a highly harmful and frequently-occurring infectious disease in the poultry industry. It occurs all over the world, and the morbidity and mortality of chickens under 10 months of age are the highest. Therefore, it was once considered to be the only Chicks are infected. In the late 1980s, people had a new understanding of the pathogenesis of pullorum. Not only young chickens are susceptible to this disease, but also young chickens aged 50 to 120 days often have outbreaks. The harm of the disease can run through the whole growth process of the chicken, and the fatality rate is as high as 50% to 60%. It is one of the most harmful infectious diseases in the poultry industry. [0003] The pathogen of pullorum is Salmonella pullor...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A23K1/18A61P31/04A61K35/37A61K35/57
Inventor 黄河李鑫
Owner SHANDONG NEW HOPE LIUHE GROUP
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