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Elastic shape memory recyclable bracket and manufacturing method and using method thereof

An elastic and memory technology, applied in the field of medical devices, can solve problems such as recyclable stents that have not yet been seen, and achieve the effects of reducing medical burden, simple manufacturing process, and low cost

Inactive Publication Date: 2012-11-07
UNIV OF SHANGHAI FOR SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there have been no reports of using shape memory polymer materials to make recyclable scaffolds in vivo

Method used

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  • Elastic shape memory recyclable bracket and manufacturing method and using method thereof
  • Elastic shape memory recyclable bracket and manufacturing method and using method thereof
  • Elastic shape memory recyclable bracket and manufacturing method and using method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Process a star-shaped mold, put polyurethane particles with a glass transition temperature (i.e. shape memory recovery temperature) of 39°C into the mold, pressurize it at a temperature higher than its melting point, and make a star-shaped bracket after demolding 1 ,like figure 1 shown.

[0039] At a temperature 15°C higher than its glass transition temperature, the star-shaped stent 1 is expanded into a tubular stent 1 by expanding the balloon 2, such as figure 2 and image 3 shown. and then cooled to room temperature, the scaffold will remain tubular, as Figure 4 shown.

[0040] After the tubular stent is sterilized, it is vacuum-dried and sealed for future use.

[0041] During use, the tubular stent is compressed into a catheter by utilizing the elasticity of polyurethane, and delivered to the diseased part 3 in the body. When the catheter is removed, the stent 1 will expand in the form of a tube at the diseased part through the recovery of elastic deformation...

Embodiment 2

[0044] Process a star mold.

[0045] Magnetic Fe 3 o 4 The micropowder was uniformly mixed into the polyurethane solution with a glass transition temperature (i.e. shape memory recovery temperature) of 39°C by ultrasonic oscillation, Fe 3 o 4 The weight percentage of fine powder and polyurethane is 5:95.

[0046] Pour the above mixed liquid into the mold, heat it to 80°C to make it solidify and form, and after demolding, the Fe-containing 3 o 4 Micronized star holder.

[0047] At a temperature 15°C higher than the glass transition temperature of polyurethane, the Fe-containing 3 o 4 The micropowdered star-shaped scaffold expanded into a tubular shape, and then cooled to room temperature, the scaffold will remain tubular.

[0048] will contain Fe 3 o 4 After the micropowdered tubular stent is sterilized, it is vacuum-dried and sealed for future use.

[0049] In use, the elasticity of polyurethane will contain Fe 3 o 4The micropowdered tubular stent is compressed in...

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Abstract

The invention relates to an elastic shape memory recyclable bracket, which is a tubular structural element manufactured by 80-100 parts of elastic shape memory polymer material and 0-20 parts of biocompatible micro powder (part by weight); a manufacturing method comprises the following steps: manufacturing raw materials as a folding-shaped bracket by a mould and expanding the folding-shaped bracket to form a tubular bracket through a ball expansion method; a using method comprises the following steps: compressing the tubular bracket in a catheter so as to transport to an internal lesion part; removing the catheter so that a bracket is restored into a tube shape; heating the tubular bracket to a shape memory restring temperature at withdrawing time; and restoring the bracket from the tube shape into an initial folding shape, thus, withdrawing the bracket conveniently. According to the invention, the manufacturing material of the bracket is polymer material with biocompatibility and / or biodegradability and has little stimulation for tissues; relatively to a metal bracket, the elastic shape memory recyclable bracket is characterized by simple manufacturing technology and low cost; in addition, therapeutic medicines are coated on the surface of the bracket so as to further enhance therapeutic effect.

Description

technical field [0001] The invention relates to a medical device, in particular to a retrievable support with elastic shape memory, a manufacturing method and a using method thereof. Background technique [0002] Implantable stents are widely used in the treatment of airway organic stenosis, esophageal cancer, bladder / prostate cancer and other diseases. In many clinical cases, the implantation of stents is temporary. With the treatment of the primary lesion and the degree of blockage in the stenosis is alleviated, the stent needs to be recovered. [0003] Existing implantable stents in the body are mainly made of stainless steel, NiTi alloy and other materials. These stents basically utilize the superelasticity of the stent material or stent structure, and the stent itself can self-expand, but cannot self-contract. The process of stent implantation is basically to compress it in a catheter and deliver it to the lesion in the body. After the catheter is removed to release th...

Claims

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Application Information

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IPC IPC(8): A61F2/82A61L31/14A61L31/12
Inventor 崔海坡宋成利黄为民
Owner UNIV OF SHANGHAI FOR SCI & TECH
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