Traditional Chinese medical composition for treatment of toxocara canis diseasees

A composition and bow-shaped technology, applied in the field of traditional Chinese veterinary medicine, can solve problems such as easy residue, large tissue irritation, and large liver and kidney side effects, and achieve the effect of strong deworming effect, small toxic and side effects, and remarkable curative effect

Inactive Publication Date: 2014-08-13
TIANJIN BIJIA PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Treatment method, the current common treatment method is to use sulfonamide drugs. Although these drugs have a certain effect, intramuscular injection is more irritating to the tissue, and intravenous injection is not conducive to the operation of dogs and cats, and the course of treatment is longer, and it is effective. slow
Sulfonamides have serious side effects on the liver and kidneys, and long-term use of such drugs can cause some bacteria to develop drug-resistant strains
At the same time, the use of sulfa drugs tends to remain in dog products and cause direct harm to humans.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A resident bought back 5 6-month-old pet dogs from other places a week ago. When walking the dogs, he found that 2 dogs were in poor spirits, and then their appetite decreased, and they developed symptoms such as cough and high fever. After treatment, they did not improve; they used Wulian serum , Amikacin, aminopyrine, 1 dog died after 5 days.

[0028] Clinical symptoms

[0029] The sick dog was depressed, with obvious loss of appetite. At the beginning of the disease, the body temperature was 40.0-41.5°C. After staying in high temperature for 2 days, it dropped slightly, with dyspnea, purulent secretions in the eyes and nose, and initial constipation. After 2-3 days, it began to have diarrhea and vomiting. Visible mucous membranes are pale, surface lymph nodes are swollen, paralysis and movement disorders appear in the later stage of the course of the disease, and finally the appetite is lost, and the patient is lying on the ground.

[0030] pathogenic mechanism

[...

Embodiment 2

[0047] The affected dog is depressed, the coat is messy and dull, the body is emaciated, and the walking gait is unstable and swaying. Body temperature 40.2°C, loss of appetite, pale visible mucous membranes, sunken eyeballs, decreased skin elasticity, half-closed eyes, yellow purulent secretions attached to the corners of the eyes, dry nose, yellow purulent secretions flowing from the nasal cavity, constricting the nostrils clogged. And cough. The breathing is shallow and fast, showing obvious abdominal breathing. Lung auscultation revealed rough breath sounds with moist rales. Heart auscultation, fast and weak heartbeat, irregular heartbeat. The affected dog also vomited frequently. The vomit was undigested chyme at first, followed by gastric juice with foam and mucus and yellow-green bile, accompanied by watery hemorrhagic diarrhea and tenesmus. Urinary oliguria and dark yellow urine. The lymph nodes on the body surface were swollen, and there were visible purplish red...

Embodiment 3

[0059] Incidence

[0060] In February 2009, 115 meat dogs raised by a meat dog breeder had an outbreak of diseases mainly including elevated body temperature, dyspnea, and neurological symptoms, with a morbidity rate of 67% and a mortality rate of 34%. Among them, all young meat dogs are ill, and their mortality rate is relatively high, accounting for 78% of the total number of dead meat dogs.

[0061] Clinical symptoms

[0062] The main manifestations of sick dogs are central nervous disorder, restlessness, loss of appetite or food refusal, dry feces, ataxia, and finally convulsions and death; The course of disease varies in length, ranging from 1 to 2 days to 1 to 3 weeks. After the onset, treatment with gentamicin, ribavirin, Folium folium, etc. was ineffective.

[0063] Pathological autopsy changes

[0064] Autopsies were carried out on the 7 dead meat dogs, and it was found that the liver was light yellow or dark brown red, and the texture was fragile, with bleeding s...

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PUM

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Abstract

The invention provides a traditional Chinese medical composition for treatment of toxocara canis diseases. The traditional Chinese medical composition comprises the following components by weight: 5-500 parts of artemisia apiacea, 5-500 parts of artemisia argyi, 5-500 parts of artemisia capillaries, 3-350 parts of quispualis indica, 3-350 parts of wine-soaked antifeverile dichroa root, 3-350 parts of areca catechu, 3-300 parts of rheum officinale, 1-150 parts of cortex phellodendri, 1-150 parts of radix scutellariae and 2-200 parts of liquorice. According to the scheme, the artemisia apiacea is bitter, cold and spicy and has the effects of eliminating asthenic fever, cooling blood and removing pathogenic factors; the artemisia argyi has the effects of eliminating dampness, killing worms and relieving itching; the artemisia capillaries is bitter and slightly cold and has the effects of clearing away heat, promoting diuresis and removing jaundice; the quispualis indica is sweet and fragrant and has the effects of killing worms and removing food retention; the wine-soaked antifeverile dichroa root is always used together with the areca catechu, has the effects of clearing cold and heat and also has strong deworming effects, and the areca catechu has good effects of killing worms, has strong potency and can be used for alleviating diarrhoea and promoting discharge of toxocara canis worms; and toxocara canis diseases can be effectively treated due to common effects of the above materials and the rheum officinale, cortex phellodendri and radix scutellariae.

Description

technical field [0001] The invention belongs to the field of traditional Chinese veterinary medicine, in particular to a traditional Chinese medicine composition for treating canine toxoplasmosis. Background technique [0002] Toxoplasmosis, formerly known as toxoplasmosis and toxoplasmosis, is a parasitic intracellular protozoan disease caused by Toxoplasma gondii of the class Sporozoa, Sarcocytidae, and Toxoplasma. The disease is a zoonosis, with cats as its final host and humans, livestock, poultry and other animals as intermediate hosts. Toxoplasmosis is extremely harmful, and it can cause premature delivery, miscarriage, and fetal malformation in pregnant women. It is one of the main causes of death in immunocompromised patients (such as AIDS patients, organ transplant patients, tumor patients, etc.) , heart, lung, eye, skin and other tissues. [0003] Dogs and cats are more commonly infected with toxoplasmosis. According to epidemiological surveys of toxoplasmosis i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61P33/02
Inventor 裴毅元军英要瑞丽鞠伯艳李帆帆王现刚郑艾斌刘永康范培松
Owner TIANJIN BIJIA PHARMA CO LTD
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