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Method for refining gardenia yellow pigment by adopting solvent crystallization

A gardenia yellow pigment and crystallization technology, which is applied in the field of purification and refinement of food coloring, can solve the problems of affecting product color price, high production cost, complicated process, etc., achieves remarkable impurity removal effect, improves color price, and is easy to crystallize Effect

Active Publication Date: 2013-12-18
苏州衷中医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this method, it is difficult to completely separate gardenia yellow pigment from water-soluble impurities with macroporous adsorption resin, and there are still impurities other than geniposide and chlorogenic acid, which are difficult to be removed by hot ethyl acetate extraction, which affects the final product The color price of the patent, and the production cost of this patent is relatively high due to the complicated process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Take 1.5 kg of gardenia coarse powder, add 15 L of water, heat and extract at 80 ° C for 1.5 hours, centrifuge the extract, add 10 L of water to the residue, heat and extract for 1 hour, centrifuge the extract, combine the extracts and concentrate to obtain 230 g of thick extract, The thick extract is the crude product of gardenia yellow pigment.

[0028] Add 1500ml, 95% ethanol aqueous solution to 230g of the crude gardenia yellow pigment, heat to 60°C to dissolve the crude gardenia yellow pigment, filter to remove insoluble impurities, concentrate the filtrate to about 400ml under reduced pressure, and store it in the refrigerator (2-8 ℃) placed for 6 hours to crystallize, crystals were precipitated, and the crystals were collected by filtration. Take 600ml, 95% ethanol aqueous solution to dissolve the crystals, filter to remove insoluble impurities, concentrate the filtrate to about 250ml under reduced pressure, place it in the refrigerator (2-8°C) for 12 hours to cr...

Embodiment 2

[0030]Take 1.5kg of gardenia coarse powder, add 15L of water, heat and extract at 80°C for 1.5 hours, centrifuge the extract, add 10L of water to the residue, heat and extract for 1 hour, centrifuge the extract, combine the extracts and concentrate them into a thick extract 223g, The thick extract is the crude product of gardenia yellow pigment.

[0031] Add 2000ml of acetone to 223g of crude gardenia yellow pigment, heat to 40°C to dissolve the crude gardenia yellow pigment, filter while hot to remove insoluble impurities, concentrate the filtrate to about 450ml under reduced pressure, and place it at -15°C for 2 hours to crystallize. Crystals were precipitated, and the crystals were collected by filtration. Take 600ml of acetone to dissolve the crystals, heat to dissolve at 40°C, filter while hot to remove insoluble impurities, concentrate the filtrate to about 300ml under reduced pressure, place at -5°C for 2 hours to crystallize, precipitate crystals, and collect crystals ...

Embodiment 3

[0033] Take 1.5 kg of gardenia coarse powder, add 15 L of water, heat and extract for 1.5 hours, centrifuge the extract, add 10 L of water to the residue, heat and extract for 1 hour, centrifuge the extract, combine the extracts and concentrate to obtain 220 g of thick extract. It is the crude product of gardenia yellow pigment.

[0034] Add 1500ml, 90% isopropanol aqueous solution to 220g of crude gardenia yellow pigment, heat to 60°C to dissolve the crude gardenia yellow pigment, filter to remove insoluble impurities, concentrate the filtrate to 500ml under reduced pressure, and place it at -20°C for 3 Hours of crystallization, crystallization. Add crystals to 500ml, 90% isopropanol aqueous solution, heat to dissolve at 60°C, filter to remove insoluble impurities, and concentrate the filtrate to 250ml under reduced pressure to obtain a color value of 288, A 238 / A 440 = 0.15, A 325 / A 440 =0.12 gardenia yellow pigment 12.9g.

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PUM

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Abstract

The invention provides a method for refining a gardenia yellow pigment by adopting solvent crystallization, belonging to the field of plant extraction. The method comprises the following steps of: adding a solvent A into a gardenia yellow pigment crude product, stirring at 10 to 30 DEG C to dissolve the gardenia yellow pigment crude product or heating to 35 to 100 DEG C to dissolve the gardenia yellow pigment crude product, and filtering and taking filtrate, wherein the solvent A consists of 70 to 100 percent of a hydrophilic organic solvent and 0 to 30 percent of water; and crystallizing the filtrate, and drying to obtain the gardenia yellow pigment. According to the gardenia yellow pigment prepared by the method, the color value is more than 200, and the A238 / A440 and A325 / A440 are smaller than 0.2. The gardenia yellow pigment prepared by the method is applied to preparation of foods, healthcare foods, cosmetics, pharmaceutical compositions and saffron monomer compounds.

Description

technical field [0001] The invention relates to the purification and refinement of edible pigments, more precisely, to further refining the crude gardenia yellow pigment to increase the color value, and removing impurities such as geniposide and chlorogenic acid to obtain high-quality gardenia yellow pigment. Background technique [0002] Gardenia yellow pigment is a kind of natural water-soluble yellow pigment extracted from Rubiaceae gardenia fruit, and its main components are carotenoid crocetin and crocetin. Scholars at home and abroad have conducted a lot of research on gardenia yellow pigment, and found that it has the functions of clearing away heat and fire, cooling blood and promoting gallbladder, lowering cholesterol and anti-cancer health care. As a natural food coloring, gardenia yellow is bright in color, non-toxic, good in stability and strong in dyeing ability, and is widely used in the fields of food, medicine and cosmetics. [0003] At present, the gardenia...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C09B61/00C09B67/54
Inventor 石荣火陈文星叶华
Owner 苏州衷中医药科技有限公司