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Turpinia arguta leaf ethanol reflux extract, preparation method and uses thereof

A technology of ethanol reflux extraction and round leaves of Shanxiang, which is applied in the direction of pharmaceutical formulas, plant raw materials, medical preparations containing active ingredients, etc., can solve the problems of high prices, reduce infection, prevent and treat influenza and its complications, The effect of inhibiting replication

Inactive Publication Date: 2013-02-13
JIANGXI SHANXIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine "Oseltamivir Phosphate (Tamiflu, (3R, 4R, 5S)-4-Acetamide-5-Amino-3(1-Propoxyethyl)-1-Cyclohexene-1 Carboxylic Acid Ethyl Phosphate "Salt)" is a neuraminidase inhibitor, which has a specific inhibitory effect on the entry of influenza virus into cells, but it is not only expensive, but also some patients experience vomiting, nausea, insomnia, headache, abdominal pain, diarrhea, dizziness, fatigue, Side effects such as nasal congestion, sore throat, and coughing

Method used

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  • Turpinia arguta leaf ethanol reflux extract, preparation method and uses thereof
  • Turpinia arguta leaf ethanol reflux extract, preparation method and uses thereof
  • Turpinia arguta leaf ethanol reflux extract, preparation method and uses thereof

Examples

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Effect test

Embodiment 1

[0025] Preparation method: take the round leaves of Cymbidium sinensis, add 13 times the amount of 45% ethanol to reflux extraction for 3 times, each time reflux extraction for 2.5 hours, filter; combine the filtrates, concentrate under reduced pressure to a thick paste or dry to obtain the ethanol reflux extract of Cymbidium sinensis.

Embodiment 2

[0027] Preparation method: Take the round leaves of Cymbidium sinensis, add 11 times the amount of 50% ethanol to reflux extraction for 3 times, each time reflux extraction for 2 hours, filter; combine the filtrates, concentrate under reduced pressure to a thick paste or dry to obtain the ethanol reflux extract of Cymbidium sinensis.

Embodiment 3

[0029] Preparation method: take the round leaves of Cymbidium sinensis, add 12 times the amount of 70% ethanol to reflux extraction for 3 times, each time reflux extraction for 2 hours, filter; combine the filtrates, concentrate under reduced pressure to a thick paste or dry to obtain the ethanol reflux extract of Cymbidium sinensis.

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Abstract

The present invention relates to uses of a turpinia ternate leaf ethanol reflux extract in preparation of drugs for neuraminidase inhibition, wherein the turpinia ternate leaf ethanol reflux extract is prepared by adding ethanol to turpinia ternate leaves and carrying out extraction. The concrete extraction method comprises: taking turpinia ternate leaves; adding 40-85% ethanol in a Turpinia arguta / ethanol (W / V) ratio of 1:5-13) to carry out reflux extraction 2-3 times, wherein each reflux extraction is performed for 1-2.5 hours; filtering; mixing the obtained filtrates; and carrying out reduced pressure concentration to obtain a thick paste or drying to obtain the turpinia ternate leaf ethanol reflux extract.

Description

technical field [0001] The present invention relates to an ethanol reflux extract of syringa rotundum and its preparation method and application. Background technique [0002] At present, influenza virus is becoming more and more serious, and influenza virus is closely related to respiratory diseases and systemic diseases caused by it. my country is one of the countries with high incidence of influenza. Not only has a large population, but also living habits are conducive to the transmission of influenza virus. The average number of episodes ranged from 0.3 to 0.7, and 2 to 4 in key groups. Influenza poses a serious threat to human beings, especially the emerging strains of influenza virus, which not only cause secondary infections of other microorganisms, but also directly lead to organ damage and allergic reactions leading to death. But there is no effective method and treatment means for treating influenza virus and its disease (influenza) at present, such as treating the...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P31/16A61K127/00
Inventor 唐春山王燕平张华敏谢宁吕武清杨小玲刘地发李志勇程帆
Owner JIANGXI SHANXIANG PHARMA
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