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Chinese medicinal composition for treating chronic gastritis as well as preparation method and application

A technology of chronic gastritis and composition, which is applied in the field of traditional Chinese medicine, can solve the problems of decreased drug absorption, decreased bioavailability, and decreased content of active ingredients, and achieve the effects of reducing inflammatory damage, inhibiting acute attacks, and improving damage effects

Inactive Publication Date: 2013-05-01
江西中医药高等专科学校
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the prior art, "A Traditional Chinese Medicine Composition for Treating Gastritis and Its Preparation Method" CN1919331 ignores that "cold evil invading the stomach" is the cause of epigastric pain One of the main reasons is to regulate qi, invigorate the middle, and dispel dampness as the treatment principle. If the external pathogens are not eliminated but only regulate qi and invigorate the middle, the clinical efficacy may not be guaranteed; in the etiology and pathogenesis of epigastric pain, cold pathogens, diet Emotions and emotions are all inducing factors, and the root of the disease is weakness of the spleen and stomach. "A Chinese Medicine for Stomach Diseases" CN101332285A proposes the treatment methods of resolving stagnation and moistening dryness, reducing qi and removing dampness, soothing the liver and harmonizing the stomach, and only emphasizing that emotions and diet are pathogenic. Ignoring the root cause of spleen and stomach weakness and the predisposing factors cold evil; because most chronic gastritis has a long course of disease and easily leads to the symptoms of spleen and stomach weakness, "A Traditional Chinese Medicine Composition for Treating Chronic Gastritis" CN102397516A fully considers cold evil, The influence of emotions in the pathogenesis of epigastric pain, but neglecting the principle of invigorating the spleen and replenishing qi to correct the weakness of the spleen and stomach
[0007]Before Chinese medicine decoction pieces are prepared into various dosage forms, they generally need to go through pretreatment processes such as extraction and separation, concentration and drying, all of which are accompanied by a long heating process, which is easy to cause Changes in chemical composition, especially traditional Chinese medicines rich in heat-unstable or volatile components, lead to a decrease in the content of active ingredients, thereby reducing drug absorption, bioavailability, and drug efficacy
At the same time, due to the complex process and long operation time, the production efficiency decreases, which leads to a substantial increase in production costs, which affects the economic benefits and sustainable development capabilities of enterprises.

Method used

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  • Chinese medicinal composition for treating chronic gastritis as well as preparation method and application
  • Chinese medicinal composition for treating chronic gastritis as well as preparation method and application

Examples

Experimental program
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Effect test

Embodiment 1

[0028] The raw materials of each component by weight are: 12 parts of heterophylla, 15 parts of Atractylodes macrocephala, 15 parts of Poria cocos, 10 parts of Jiang Pinellia, 3 parts of Evodia rutaecarpa, 10 parts of Bupleurum bupleuri, 12 parts of August root, 4 parts of dried ginger, and 15 parts of Citrus aurantium. 8 parts of tangerine peel, 8 parts of magnolia bark, 10 parts of scutellaria baicalensis, 4 parts of berberine, 15 parts of octopus, 12 parts of corydalis, and 15 parts of baiji.

Embodiment 2

[0030] The raw materials of each component by weight are: 10 parts of heterophylla, 20 parts of Atractylodes macrocephala, 20 parts of Poria cocos, 10 parts of Jiang Pinellia, 4 parts of Evodia rutaecarpa, 12 parts of Bupleurum bupleuri, 15 parts of August root, 2 parts of dried ginger, and 18 parts of Citrus aurantium. 10 parts of tangerine peel, 10 parts of magnolia bark, 9 parts of scutellaria baicalensis, 5 parts of berberine, 12 parts of squid octopus, 15 parts of Corydalis Corydalis, and 16 parts of white root.

Embodiment 3

[0032] The raw materials of each component by weight are: 14 parts of heterophylla, 14 parts of Atractylodes macrocephala, 16 parts of Poria cocos, 8 parts of Jiang Pinellia, 2 parts of Evodia rutaecarpa, 8 parts of Bupleurum, 10 parts of August root, 4 parts of dried ginger, and 12 parts of Citrus aurantium. 9 parts of tangerine peel, 9 parts of magnolia bark, 12 parts of scutellaria baicalensis, 4 parts of berberine, 18 parts of octopus, 18 parts of corydalis, 15 parts of baiji.

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Abstract

The invention discloses a Chinese medicinal composition for treating chronic gastritis. The Chinese medicinal composition is characterized by comprising the following bulk pharmaceutical herbs in parts by weight: 10-14 parts of heterophylly falsestarwort root, 10-20 parts of white atractylodes rhizome, 10-20 parts of poria cocos, 8-12 parts of ginger processed pinellia, 1-5 parts of medicinal evodia fruit, 8-12 parts of Chinese thorowax root, 8-16 parts of akebia fruit, 2-6 parts of dried ginger, 10-20 parts of immature bitter orange, 6-10 parts of dried tangerine or orange peel, 6-10 parts of officinal magnolia bark, 8-12 parts of baical skullcap root, 2-6 parts of coptis root, 12-18 parts of cuttlefish bone, 9-15 parts of corydalis tuber, and 12-18 parts of common bletilla pseudobulb. A better effect can be achieved by adding notholirion bulbuliferum, bract machilus bark, angelica polymorpha Maxim and lovely hemsleya root. Meanwhile, a modern superfine grinding technology and a cell disruption technology are adopted to prepare Chinese medicinal superfine powder, and the Chinese medicinal composition can be orally taken directly or taken after being mixed with boiled water, can be used to rapidly alleviate symptoms of the chronic gastritis, has stronger effects of invigorating spleen, supplementing qi, warming and harmonizing stomach, and promoting qi circulation to relieve pain, treats both symptoms and root causes, has a rapid curative effect, and is convenient to produce and take and low in preparation cost at the same time, thereby having good popularization values.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating chronic gastritis, a preparation method and application thereof, and belongs to the field of traditional Chinese medicines. Background technique [0002] Chronic gastritis refers to the chronic inflammatory changes of the gastric mucosa caused by various reasons. It is a common disease and frequently-occurring disease. Intensified, the incidence of chronic gastritis has a rising trend. Although the incidence in a large population has not been reported, it is generally believed that its incidence increases with age. According to data, 47% of people aged 20 to 40 have normal gastric mucosa, while only 18% of people over 60 years old are in the normal range. In the autopsy of the elderly, it is very common to be complicated by chronic gastritis. There are foreign reports that the incidence of this disease may account for 30% of the total population. Although there is no r...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/04
Inventor 陈建章王小平
Owner 江西中医药高等专科学校
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