Traditional Chinese medicine composition resistant to NDM-1 medicine resistant gene bacteria (superbacteria)

Abstract

The invention provides a medicine composition taking medicines which benefit qi and activate blood circulation and clear away heat and toxic materials for compatibility. The medicine composition has exact treatment effects on various inflammations caused by standard bacteria strains and medicine resistant strains (such as KPC positive or superbacteria NDM-1 positive) such as respiratory tract infection, pelvic cavity infection, urinary infection and acute peritonitis. The medicine composition is a combined preparation of one or more of radix astragali, ginseng, American ginseng, dangshen, heterophylly falsestarwort root, largehead atractylodes rhizome, liquorice and Chinese yam, one or more of salvia miltiorrhiza, red peony root, leeches, Sichuan lovage rhizome, safflower, peach kernels, pseudo-ginseng, rosewood, rhizoma corydalis, ground beetle, motherwort herb, Chinese angelica and giant knotweed rhizome and one or more of honeysuckle, weeping forsythia capsule, isatis root, dyers woad leaf, dandelion, baical skullcap root, heartleaf houttuynia herb, dahurian patrinia herb, common andrographis herb, Tokyo violet herb, herba corydalis bungeanae, gueldenstaedtia multiflora bunge, globeflower and wild chrysanthemum in clinically reasonable doses.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition containing an anti-standard bacterial strain (antibiotic-sensitive bacterial strain), KPC-positive and NDM-1 drug-resistant gene bacteria (commonly known as super bacteria) and a preparation method thereof. It belongs to the field of pharmaceutical preparations. Background technique [0002] Since the invention of antibiotics, it has brought a turning point to people's lives, and human infectious diseases have been effectively controlled. However, due to the abuse of antibiotics by humans, more and more drug-resistant strains have emerged. For example, Staphylococcus aureus is a common bacteria that can cause skin, lung, blood, and joint infections. At first, penicillin was effective. After the mutation, it is no longer sensitive to penicillin and methicillin (semi-synthetic penicillin). This hard-to-kill drug-resistant bacteria is called MRSA. In August 2010, a super bacteria mor...

AI Technical Summary

Problems solved by technology

However, once tested by the gold standard of in vivo antibacterial experiments of western medicine antibiotics, these Chinese patent medicines have shown no effect or weak curative effect. Strong drugs are less likely to show efficacy in this model

Therefore, after reviewing the literature, no antibacterial experiments in animals were found in which the above-mentioned marketed Chinese patent medicines and antibiotics were used as controls.

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