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Composition for promoting opening of skin aquaporin and preparation method thereof

A channel protein and skin water technology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., to prevent and combat skin aging, prevent and combat dry skin and mucous membranes, and promote the opening of skin aquaporins

Active Publication Date: 2013-09-25
SHENZHEN GENE BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the prior art lacks products capable of promoting or positively affecting the autologous improved hydration of the stratum corneum

Method used

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  • Composition for promoting opening of skin aquaporin and preparation method thereof
  • Composition for promoting opening of skin aquaporin and preparation method thereof
  • Composition for promoting opening of skin aquaporin and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The composition for promoting the opening of skin aquaporin according to the present invention comprises the following components in proportion by weight: 53.17 parts of deionized water, 3.50 parts of glycerin, 0.02 parts of carbomer, 0.01 part of xanthan gum, 0.01 part of EDTA 0.02 parts of sodium, 0.05 parts of allantoin, 1.00 parts of urea, 0.20 parts of vitamin B5, 0.20 parts of betaine, 0.50 parts of trehalose, 0.50 parts of fiber sugar, 0.50 parts of taurine, lauryl Mammary gland sodium lactate is 0.20 parts, monomethylsilanetriol is 1.00 parts, hydroxyproline is 1.00 parts, aspartic acid is 1.00 parts, yeast amino acid is 0.50 parts, polyglutamic acid is 0.01 parts, sodium hyaluronate 0.01 part of dipotassium glycyrrhizinate, 0.01 part of dipotassium glycyrrhizinate, 1.50 parts of purslane extract, 1.30 parts of licorice extract, 0.001 part of ceramide 3, 0.001 part of ceramide 6, 0.001 part of ceramide 1, plant 0.05 parts of sphingosine, 0.10 parts of cholestero...

Embodiment 2

[0033]The composition for promoting the opening of skin aquaporin according to the present invention comprises the following components in proportion by weight: 76.67 parts of deionized water, 4.50 parts of glycerin, 0.04 parts of carbomer, 0.04 parts of xanthan gum, EDTA 0.10 parts of sodium, 0.20 parts of allantoin, 5.00 parts of urea, 1.00 parts of vitamin B5, 2.00 parts of betaine, 2.00 parts of trehalose, 1.50 parts of fiber sugar, 1.00 parts of taurine, lauryl Mammary gland sodium lactate is 0.40 parts, monomethylsilanetriol is 2.00 parts, hydroxyproline is 3.00 parts, aspartic acid is 2.00 parts, yeast amino acid is 4.00 parts, polyglutamic acid is 0.10 parts, sodium hyaluronate 0.10 parts of dipotassium glycyrrhizinate, 0.40 parts of dipotassium glycyrrhizinate, 5.50 parts of purslane extract, 2.30 parts of licorice extract, 0.01 parts of ceramide 3, 0.02 parts of ceramide 6, 0.02 parts of ceramide 1, plant 0.12 parts of sphingosine, 0.30 parts of cholesterol, 0.08 par...

Embodiment 3

[0041] The composition for promoting the opening of skin aquaporin according to the present invention comprises the following components in proportion by weight: 60 parts of deionized water, 4.00 parts of glycerin, 0.03 parts of carbomer, 0.03 parts of xanthan gum, EDTA 0.05 parts of sodium, 0.10 parts of allantoin, 2.00 parts of urea, 0.50 parts of vitamin B5, 1.00 parts of betaine, 1.00 parts of trehalose, 0.80 parts of fiber sugar, 0.80 parts of taurine, lauryl Mammary gland sodium lactate is 0.30 parts, monomethylsilanetriol is 1.50 parts, hydroxyproline is 1.50 parts, aspartic acid is 1.50 parts, yeast amino acid is 2.50 parts, polyglutamic acid is 0.05 parts, sodium hyaluronate 0.05 parts of dipotassium glycyrrhizinate, 0.10 parts of dipotassium glycyrrhizinate, 2.50 parts of purslane extract, 1.50 parts of licorice extract, 0.008 parts of ceramide 3, 0.008 parts of ceramide 6, 0.008 parts of ceramide 1, plant 0.08 parts of sphingosine, 0.20 parts of cholesterol, 0.03 pa...

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Abstract

The invention particularly discloses a composition for promoting opening of skin aquaporin, which is mainly proportionally prepared from deionized water, glycerol, carbomer, xanthan gum, lycine, trehalose, inositol, taurine, lauryl mammary gland sodium lactate, monomethyl-monosilane triol, oxyproline, aspartic acid, yeast amino acid, polyglutamic acid, sodium hyaluronate, dipotassium glycyrrhetate, purslane extracting solution, licorice extract, ceramide, phytosphingosine, cholesterol, oligopeptide-1, polyquaternary amine salt-14 and the like. The composition has the function of promoting opening of skin aquaporin, has better water replenishing and locking effect, and effectively prevents and resists the phenomena of dry skin mucosa and skin aging.

Description

technical field [0001] The invention relates to a composition for promoting skin water molecule transportation, in particular to a composition for promoting opening of skin water channel protein and a preparation method thereof. Background technique [0002] Hydration of the stratum corneum, the outermost layer of the skin, is important for both skin appearance and physiology. Hydration of the stratum corneum is determined by several factors, such as ambient humidity, skin structure, fat and protein content, barrier properties, and some substances with moisturizing effects. The response of keratinocytes to these factors plays a decisive role. [0003] Aquaporin-3 (AQP3) is a bifunctional water channel that can transport both water molecules and small molecules such as glycerol. AQP3-mediated glycerol transport in skin keratinocytes is of great significance to skin function, and its functional defect can lead to skin damage such as dry skin, decreased elasticity and weakene...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/60A61K8/42A61K8/41A61K8/40A61K8/64A61Q19/00A61Q19/08
Inventor 杨平顺张泽奇
Owner SHENZHEN GENE BIOLOGICAL TECH
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