Traditional Chinese medicine extract for treating stagnation of blood stasis as well as preparation and preparation method thereof

A blood stasis internal resistance and extract technology, which is applied in the field of traditional Chinese medicine extracts for the treatment of blood stasis internal resistance, can solve the problems of large single dose, large side effects, and low purity of active ingredients, so as to increase dissolution and reduce hygroscopicity , Improve the effect of bioavailability

Active Publication Date: 2013-12-25
陈有才
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, Chinese patent medicines are mostly used for the treatment of cardiovascular and cerebrovascular diseases. For example, CN1334121 discloses a Tongxinluo pharmaceutical composition, which includes Codonopsis Radix, Radix Pseudostellariae, Radix Astragali, Atractylodes Rhizoma Atractylodes Rhizome and Radix Glycyrrhizae. One or more; one or more of 56 herbs such as leech, salvia, Chuanxiong, safflower, red peony, jiangxiang, notoginseng, turmeric, peach kernel, etc., and one of scorpion, cicada slough, and centipede One or more combination preparations, including the highly toxic animal medicines scorpion, cicada slough or centipede that play an irreplaceable role in the combination preparation; CN1457831 discloses a kind of medicine for treating cardiovascular and cerebrovascular diseases, and the raw material drug is composed of It is made of 55 raw materials such as safflower, Sichuan Achyranthes bidentata, papaya, astragalus, turmeric, licorice, and ginseng; , Ophiopogon japonicus, and honey-roasted licorice. The above traditional Chinese medicine compositions are all directly used as raw materials without treatment of the raw materials. As a result, the purity of the active ingredients in the composition is not high, and the single dose is large. , technical problems such as large side effects

Method used

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  • Traditional Chinese medicine extract for treating stagnation of blood stasis as well as preparation and preparation method thereof
  • Traditional Chinese medicine extract for treating stagnation of blood stasis as well as preparation and preparation method thereof
  • Traditional Chinese medicine extract for treating stagnation of blood stasis as well as preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Embodiment 1 Chinese medicine extract

[0058] Composition of Chinese herbal extracts

[0059]

[0060] Preparation:

[0061] 1) Preparation of extract A: Weigh the raw materials of ginseng, licorice, chuanxiong and achyranthes bidentata in the prescribed amount, crush them to obtain coarse powder A, add 50% ethanol aqueous solution to reflux and extract three times, and add ethanol for the first time to obtain coarse powder 15 times the weight of A, reflux for 3 hours, add ethanol for the second time to 6 times the weight of coarse powder A, reflux for 3 hours, add ethanol for the third time to 3 times the weight of coarse powder A, reflux for 2 hours, combine the reflux liquid, filter , to obtain extract A, concentrate the extract A into a thick paste, and dry to obtain extract A;

[0062] 2) Preparation of extract B: Weigh the prescribed amount of Atractylodes macrocephala, Poria cocos, peach kernel, Rehmannia glutinosa, Jiangxiang, Ophiopogon japonicus, Schisa...

Embodiment 2

[0066] Embodiment 2 Chinese medicine extract

[0067]

[0068]

[0069] Preparation:

[0070] 1) Preparation of extract A: Weigh the raw materials of ginseng, licorice, chuanxiong and achyranthes bidentata in the prescribed amount, crush them to obtain coarse powder A, add 75% ethanol aqueous solution to reflux and extract three times, and add ethanol for the first time to obtain coarse powder 10 times the weight of A, reflux for 5 hours, add ethanol for the second time to 8 times the weight of coarse powder A, reflux for 2 hours, add ethanol for the third time to 5 times the weight of coarse powder A, reflux for 1 hour, combine the reflux liquid, filter , to obtain extract A, concentrate the extract A into a thick paste, and dry to obtain extract A;

[0071] 2) Preparation of extract B: Weigh the prescribed amount of Atractylodes macrocephala, Poria cocos, peach kernel, Rehmannia glutinosa, Jiangxiang, Ophiopogon japonicus, Schisandra chinensis, Earthworm and Polygonu...

Embodiment 3

[0075] Embodiment 3 Chinese medicine extract

[0076]

[0077] Preparation method: prepare the traditional Chinese medicine extract according to the method described in Example 1.

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PUM

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Abstract

The invention relates to traditional Chinese medicine extract for treating stagnation of blood stasis as well as a preparation and a preparation method thereof. The traditional Chinese medicine extract is prepared by extracting 20 material medicines including red flowers, roots of common peony, ligusticum wallichii and the like. The traditional Chinese medicine extract has a very high curative effect for heart and cerebral vusculer diseases including cerebral infarction, coronary heart diseases and the like which are caused by stagnation of blood stasis, a small side effect and does not apply virulent animal medicines; a solid preparation prepared from the traditional Chinese medicine extract and auxiliary materials is preferably a pill or a tablet which has good stability, formability and effectiveness.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a traditional Chinese medicine extract for treating blood stasis and internal resistance, as well as its preparation and preparation method. Background technique [0002] In recent years, the incidence of cardiovascular and cerebrovascular diseases such as cerebral infarction and coronary heart disease has been increasing year by year, and it is showing a younger trend. Traditional Chinese medicine believes that it belongs to the category of "chest pain", "heartache" and "stroke". Both of these diseases are caused by internal resistance of blood stasis, mostly caused by dysfunction of viscera, or deficiency of qi and blood, combined with fatigue and internal injury, worry, anger, excessive drinking and eating, resulting in stagnation of blood stasis, phlegm and heat in the body. Accumulation, or yang transformation and wind movement, blood does not follow th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P9/10A61K35/56A61K35/62
Inventor 陈有才
Owner 陈有才
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