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Preparation method of bitter gourd peptide arabinose composite tablet

A technology of arabinose and a production method is applied in the field of production of balsam pear peptide arabinose composite tablets to achieve the effects of good effect, improving insulin sensitivity, and reducing total cholesterol and low-density lipoprotein cholesterol

Inactive Publication Date: 2014-06-18
DONGYING BEIKANG BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] But above-mentioned prior art does not add inulin, balsam pear polypeptide, phytosterol etc. in complex sugar simultaneously

Method used

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  • Preparation method of bitter gourd peptide arabinose composite tablet

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Effect test

Embodiment 1

[0011] Embodiment 1: the present invention is made of following components, and each component is calculated by weight part:

[0012] 8 parts of bitter gourd polypeptide, 15 parts of L-arabinose, 0.1 part of chromium-rich yeast, 25 parts of inulin, 5 parts of phytosterol, 10 parts of D-mannitol, 10 parts of microcrystalline cellulose, 0.5 part of magnesium stearate, 2 parts of hypromellose, among them, bitter gourd polypeptide, L-arabinose, inulin, phytosterol, D-mannitol, microcrystalline cellulose and magnesium stearate, respectively passed through a 100-mesh sieve and put into the three-dimensional Mixer; chromium-rich yeast is added to a three-dimensional mixer; after mixing in a three-dimensional mixer for 20-30 minutes, adding hypromellose binder, granulating, drying at 60-70°C for 30 minutes, granulating, and tableting to obtain compound finished tablet; the above-mentioned chromium-rich yeast is diluted by the double-dispersion method and then added to the three-di...

Embodiment 2

[0022] Embodiment 2: the present invention is made of following components, and each component is calculated by weight:

[0023] 15 parts of bitter melon polypeptide, 25 parts of L-arabinose, 0.3 parts of chromium-rich yeast, 35 parts of inulin, 15 parts of phytosterol, 15 parts of D-mannitol, 20 parts of microcrystalline cellulose, 1 part of magnesium stearate, 5 parts of hypromellose, among them, bitter gourd polypeptide, L-arabinose, inulin, phytosterol, D-mannitol, microcrystalline cellulose and magnesium stearate, respectively passed through a 100-mesh sieve and put into the three-dimensional Mixer; chromium-rich yeast is added to a three-dimensional mixer; after mixing in a three-dimensional mixer for 20-30 minutes, adding hypromellose binder, granulating, drying at 60-70°C for 30 minutes, granulating, and tableting to obtain compound finished piece.

Embodiment 3

[0024] Embodiment 3: the present invention is made of the following components, and each component is calculated according to parts by weight:

[0025] 10 parts of bitter melon polypeptide, 20 parts of L-arabinose, 0.2 parts of chromium-rich yeast, 30 parts of inulin, 10 parts of phytosterols, 12 parts of D-mannitol, 15 parts of microcrystalline cellulose, 0.7 parts of magnesium stearate, 3 parts of hypromellose, among them, bitter gourd polypeptide, L-arabinose, inulin, phytosterol, D-mannitol, microcrystalline cellulose and magnesium stearate, respectively passed through a 100-mesh sieve and put into the three-dimensional Mixer; chromium-rich yeast is added to a three-dimensional mixer; after mixing in a three-dimensional mixer for 20-30 minutes, adding hypromellose binder, granulating, drying at 60-70°C for 30 minutes, granulating, and tableting to obtain compound finished piece.

[0026] The present invention is made of a variety of ingredients beneficial to blood sugar c...

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Abstract

The invention relates to a preparation method of a bitter gourd peptide arabinose composite tablet. The bitter gourd peptide arabinose composite tablet consists of the following components in parts by weight: 8-15 parts of bitter gourd polypeptides, 15-25 parts of L-arabinose, 0.1-0.3 part of chromium-enriched yeast, 25-35 parts of inulin, 5-15 parts of phytosterol, 10-15 parts of D- mannitol, 10-20 parts of microcrystalline cellulose, 0.5-1 part of magnesium stearate, and 2-5 parts of hydroxypropyl methylcellulose. The preparation method has beneficial effects that the bitter gourd peptide arabinose composite tablet is prepared by adopting a plurality of components beneficial to blood sugar control and blood lipid metabolism; compared with a way of independently adopting the bitter gourd polypeptides, the inulin or the phytosterol, and the like, a way of combining the bitter gourd polypeptides, the inulin or the phytosterol, and the like is better in effect, beneficial to blood sugar control and blood lipid metabolism of a patient with diabetes mellitus II, and free of influences on functions of livers and kidneys. Besides, the preparation method can improve sensibility of insulin better and can remarkably lower total cholesterol and low-density lipoprotein cholesterol of the patient with diabetes mellitus II.

Description

technical field [0001] The invention relates to a preparation method of an arabinose composite tablet, in particular to a preparation method of a bitter melon peptide arabinose composite tablet. Background technique [0002] Diabetes is a worldwide epidemic disease and has become the third chronic disease that seriously threatens human health after tumors and cardiovascular diseases. According to WHO estimates, there are currently about 175 million people with diabetes in the world, and it will reach 300 million by 2025. China has become the fastest growing area of ​​diabetes patients in the world, increasing 4-5 times from the 1980s to the mid-1990s. According to incomplete statistics, China currently has 30 to 40 million diabetic patients; among the daily increasing number of diabetics, type 2 diabetes accounts for more than 90%. The main factor causing the substantial increase in patients with type II diabetes is the dramatic change in diet structure in recent years. T...

Claims

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Application Information

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IPC IPC(8): A61K38/16A61K9/20A61P3/10A61P3/06A61K31/733A61K31/7004
Inventor 李继贵赵秀河
Owner DONGYING BEIKANG BIOLOGICAL SCI & TECH
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