Mytilus edulis polysaccharide, and preparation method and application of mytilus edulis polysaccharide

A mussel polysaccharide and mussel technology, applied in the field of mussel polysaccharide and its preparation, can solve problems such as unclear chemical structure, lipid-lowering efficacy and toxicity evaluation, and achieve high purity, high safety, and prevention of hyperlipidemia Effect
CN107056962AActive Publication Date: 2017-08-18SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES
Publication Date
2017-08-18

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Abstract

The invention provides mytilus edulis polysaccharide extracted from mytilus sp., an industrial extraction method of the mytilus edulis polysaccharide, and an application of the mytilus edulis polysaccharide in preparation of antilipemic and antiatherosclerotic drugs and health food. The mytilus edulis polysaccharide takes (1-4)-alpha-D-Glc as main chains, contains (1-2)-alpha-D-Glc branches, and has a configuration of alpha-pyranoid glucan; every 12 glucose main chains averagely contain one (1-2) glucose branch; and the relative molecular weight is 800-8000KDa. The mytilus edulis polysaccharide is extracted from boiled and dried mytilus sp. by coarse extraction, enzymolysis, purification, drying and the like, and is mild in extraction condition and high in purity. The mytilus edulis polysaccharide can significantly reduce triglyceride, total cholesterol and low-density lipoprotein cholesterol, has an effect of reducing lipid, and is widely applied to preparation of drugs for treating or preventing hyperlipoidemia and atherosclerosis and preparation of antilipemic health products or special medical formula food.
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Description

technical field

[0001] The invention belongs to the field of natural product extraction and application, and relates to a mussel polysaccharide and its preparation method and application. Background technique

[0002] Hyperlipidemia caused by lipid metabolism disorders is closely related to the occurrence of cardiovascular and cerebrovascular diseases, the number one killer of human health, and is one of the most important pathogenic factors that threaten human life and health. Among the popular blood lipid-lowering drugs currently on the market, statins are the most widely used and have the best curative effect, accounting for more than 80% of the total sales of blood lipid-lowering drugs. However, statins have adverse reactions related to liver, kidney, and metabolic disorders in the body. In addition, gastrointestinal reactions, rhinitis, sinusitis, headache, sore throat, influenza syndrome, arthritis, chest pain, insomnia, and muscle toxicity are common. and other toxic...

Claims

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